ID A0A0V0Y5K0_TRIPS Unreviewed; 1924 AA.
AC A0A0V0Y5K0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Myosin-4 {ECO:0000313|EMBL:KRX94937.1};
GN Name=unc-54 {ECO:0000313|EMBL:KRX94937.1};
GN ORFNames=T4E_6285 {ECO:0000313|EMBL:KRX94937.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX94937.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX94937.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX94937.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril
CC {ECO:0000256|ARBA:ARBA00004657}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX94937.1}.
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DR EMBL; JYDU01000064; KRX94937.1; -; Genomic_DNA.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 3.
DR Gene3D; 1.20.5.370; -; 5.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF7; MYOSIN-3; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 31..80
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 84..777
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 652..674
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 870..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 901..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 941..964
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..893
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 177..184
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1924 AA; 223922 MW; A02A767213A3C04A CRC64;
MSYVNPEDDP GWQYLRQKAE QALQDQMKAY DSKKNCWIPD ATEGFIAAEI KSTKGDMITV
MSAKGNEVTL KKEMVQEMNP PKFEKTEDMA NLTFLNEASV LHNLRQRYYS MMIYTYSGLF
CVVINPYKRL PIYTESVIKL YMGRRRNEMP PHLFATSDEA YRNMVQDRAN QSMLITGESG
AGKTENTKKV IAYFAIVGAT QAAMASGDKK PQQATLEEQI VQTNPVLEAF GNAKTVRNNN
SSRFGKFIRV HFNKLGKLTG GDIEHYLLEK SRVIRQAPGE RCFHIFYQMM SGQLKGLRES
LRLTKDLRYY HFVSQAELTI DGVDDKEEMK VTDYSFDVMG FEQEEKDNLY KLCAAIMHMG
EMKFKQRPRE EQAEVDTLED AENACHCFGV NHEEFAKALI KPRVRVGTEW VNKGQNLDQA
IYSRMFHWLI VRCNKTLSMK DMEKAFFIGV LDIAGFEIFD LNSFEQLWIN FVNERLQQFF
NHHMFVLEQE EYQREGIKWE FIDFGLDLQA CIDLLEKPLG IVSMLDEECI VPKATDMTYV
QKLNDQHLGK HPNYQKAKPP KAKQAEAHFA LVHYAGTVRY NVNGWLEKNK DPLNDTAVNV
LKHANGNQLL LDIWKDYQTQ EEALEASKTG SSKKKGKSSS FMTVSMMYRE SLNNLMNMLN
STHPHFIRCI IPNEQKKSGL IEASLVLNQL TCNGVLEGIR ICRKGFPNRV QYPDFKHRYA
ILASDEAHSS EDAKVASEKM VDRMVVEKVF SEEEHRIGLT KIFFKAGVLA RLEEIRDQKL
SDILTGFQAQ ARWYLGKIDA KRREEQRTGL LIIQRNIRTW LKLRNWHWFK LYGKELEGSL
NNEEKTRKDL EGQLAKLIQE KNDLFTQLQS EKGNLSSSEE KIQKLTSQKS DLERQVNDLS
DRLNNQEERG AELQKAKKKV ESECENLNRK IQDLELSLRK AESEKQSRDN QIRSLQDEMT
SQDELAGKLN KEKKHQEEVN RKLMEDLQAE EDKVNHLNKL KSKLEQQLDD LEDSLEREKR
ARQDVEKGKR KVEGDIRVAH ENIDEINKQK HDLESNLKKK EQEMQALSSK LEDEQGLVAK
MQRQIKELQT RIQELEEELE QERQARSKSE KVRNDLQRQL EELSERLDEA GGATQAQLEM
NKKREAELAK LRRDLEEANM NHEGQLASLR KKHNDAVAEM SDQLDQEKVA YQRELEDLHA
AMDQENKAKQ DADRFSKQLE LQLAELQAKN DEQTRQLHDY TNMKNRINSE NADLMRQLED
AESQLNSLNR LKSQYQTQLE EAKRTADEET RERHNLAAQL KNMEHENQSL REQLEEEAES
KTEMQRHISK LNAEIQQWKA KFESEGLARV DEIEEAKRKL TQKVQEMQEA FEAANGKIAS
LEKIRHKLLG EIDDAQVDVE RANNYAAQLE KKQKGFDKIV DEWKKKCDDL SSELDASQRE
NRHLSTECFK LKNSQDELIE QIEAVRRENK NLVQEIKDIT DQLGEGGRSV HELQKVVRRL
ELEKEELQQA LDEAESALEA EESKVMRAQV EVSQIRQEIE KRIREKEEEF ENTRKNHQRA
LDSMQATLES EAKGRAEALR LKKKLESDIN ELEIALDHAN KANADAQKNI KMYQDQVKEL
QMHIEDEQRQ REEIREQFHA SEKRCAMLQS EKEEYMTASE QAERARRQAE AELYELREQV
NELSSTNASL SAIKRKLEGE LQALHAELDD TLNELKKVDE QCKKAMTDAA RLAEELRQEQ
EHSMHVERMR KGLEQQVKEM QVRLDEAEQA ALKGGKKIIQ KLEQRIRELE QELDLEQRRH
QETDKNMRKQ DRRIKETEFQ LEEDKKNAER MQDLIDKLQQ KLKTYKRQIE EAEELAATNL
SKYRQLQQQL EDAEERADIA ENSLAKLRAK NRSSTSVGGN MAISHSASGI LRSASRARMT
NNMD
//
