ID A0A0V0Y773_TRIPS Unreviewed; 679 AA.
AC A0A0V0Y773;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=DED1 {ECO:0000313|EMBL:KRX96120.1};
GN ORFNames=T4E_9358 {ECO:0000313|EMBL:KRX96120.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX96120.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX96120.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX96120.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX3/DED1
CC subfamily. {ECO:0000256|ARBA:ARBA00024358}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX96120.1}.
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DR EMBL; JYDU01000047; KRX96120.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0Y773; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0043186; C:P granule; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47958; ATP-DEPENDENT RNA HELICASE DBP3; 1.
DR PANTHER; PTHR47958:SF32; RNA HELICASE; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815}.
FT DOMAIN 249..277
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 317..410
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 422..583
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 585..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 249..277
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 652..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 679 AA; 76592 MW; 93C7D6E78F335E5B CRC64;
MSNYYKKGEI DVNVADKFEN LSLGVGQQAD SRAHEQLNAG PYVPPHLRQA QGVQGYSQNR
WNNSQSNGYI DMRMDSMANW QCGGPQPPKN YSRGYGRMPD NRGNFYPPNQ YDSMPAAGNR
NMRRNFGHCG GQKNDQPGNG SYRGRMGYEN REGFRSAIQY QTHRNFMPNF LPNDWTYCWP
ISQEKNVPDR WRGLRDDRGS NMQSWSEQSA RDPRLEEELF GSGNTGINFD KYEEIAVEAT
GQNVPACIQK FSELNLHPWI MDNIRLCHYD KPTPVQKFAI PTALENRDLM ACAQTGSGKT
AAFLLPILHH ILSGGPEMLR KIGCHLLVAT PGRLNDVMNQ GFIGLDACRF LVLDEADRML
DMGFEPQIRQ IVEMSGMPRR SHRQTMMFSA TFPHEIQMLA QDFLVPDYVF LAVGRVGSTS
ENITQKLVWV EDYDKRAFLL DLLNASSPET LTLIFVETKR GAADLAYFLS GERYSVVAIH
GDLKQFEREQ HLESFRSGNT PILVATAVAA RGLDIPNVKH VINYDLPSEI DEYVHRIGRT
GRVGNIGLAT TFFNNKNKNM ARDLAELLVE ANQELPDFLE RMARENPRGA QHGNRSRNQR
NFGGRDFRDQ YRSGGGNAAM HNARAVGNMY SVGGGGGGMP GGGGMGMAYG YNPRSVQQQQ
QQQQQQQRNS GNRLDWWDD
//
