ID A0A0V0YLS5_TRIPS Unreviewed; 579 AA.
AC A0A0V0YLS5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Ubiquitin-protein ligase E3B {ECO:0000313|EMBL:KRY01069.1};
DE Flags: Fragment;
GN Name=ube3b {ECO:0000313|EMBL:KRY01069.1};
GN ORFNames=T4E_2627 {ECO:0000313|EMBL:KRY01069.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRY01069.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRY01069.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRY01069.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY01069.1}.
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DR EMBL; JYDU01000005; KRY01069.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0YLS5; -.
DR STRING; 6337.A0A0V0YLS5; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700:SF3; UBIQUITIN-PROTEIN LIGASE E3B; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KRY01069.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 218..579
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT ACT_SITE 547
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY01069.1"
SQ SEQUENCE 579 AA; 67096 MW; 49B43BF71785CC9A CRC64;
LVAGDIESAV NHYLQLFVSD KTQSSAESLS FIVFFESATY LMTILDDYEL FTLEKPFQVR
QLISMAYFCN LFIFRSVWEK TVGRHILQSV KYHWLNDVLR NCTFNVVLGF LLLIYSRDCR
RPFVPKDFWL MKDLKSSVFL NEVNRGNKKA LFIIQRIPHV IPHRERIKLF RKYVASEKAS
LAAARLFEDQ MSVIITIHRA RIVEDGFRQL SQLPGRILKG IVRVKFINEQ GLDEPGIDQD
GVFKEFLEEV IKNIFDPALN LFKLTSEGHL YPSPTSYIHE NYLLLFEFIG KMLGKAVYEG
ICVDILLASF FINHLIGRTA SKYHSSIDEL SSLDADLYKQ LTFIKHYEGD MNDLGLTFAC
DEDILGEVVT HELRPGGRTI PVTKENKISY VHLMAHYRMF VQIKDQIAAF MRGFHAIISP
EWLRMFSADE FQRLLSGDTC DIDLHDLRKH TQYFGGFHNN HRVIVWLWEI LANDFSVEER
RLFLKFVTSC SKPPLLGFEY LEPPFSIRCV EVNDDEDEGD TLGSVIRGFL AIRKEDPVSR
LPTTSTCFNL LKLPNYHRKS TLRDKLRYAI HCGTGFELS
//
