ID A0A0V0ZFK3_9BILA Unreviewed; 376 AA.
AC A0A0V0ZFK3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Ubiquitin-like modifier-activating enzyme 5 {ECO:0000256|ARBA:ARBA00016279};
GN ORFNames=T12_11887 {ECO:0000313|EMBL:KRY11091.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY11091.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY11091.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY11091.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ubiquitin-activating E1 family. UBA5
CC subfamily. {ECO:0000256|ARBA:ARBA00005339}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY11091.1}.
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DR EMBL; JYDQ01000207; KRY11091.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0ZFK3; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd00757; ThiF_MoeB_HesA_family; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR PANTHER; PTHR10953:SF9; UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5; 1.
DR Pfam; PF00899; ThiF; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054783}.
FT DOMAIN 40..289
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 41888 MW; B1DB54053486484F CRC64;
MASNEICRAD KSSHGTVGTK SVRREKISEM SSEVTDSNPY SRLMALKRMG IVKNYENIRN
FTIIIVGIGG VGSVVSEMLT RCGIGKLILI DYDKVEMANM NRLFFQPHQA GMSKVEAAKT
TLQDINPDVE VDSYNCNIIT MENFNKLLHL IKCGSLHGGQ VDLVLSCVDN FEARMAINTA
CNELNQRWFE SGVSENAVSG HMQFIIPGKT ACFACAPPLV VASKIDEKTL KKEGVCAASL
PTTMGVIAGL LVQNVLKYLL KFGKVSYYLG YNSLEDFFPT YVIKPNPNCD DTICQMRQKE
FVFMLDIVLS FEEEESAEPV EMEQKSTLKH SENPWGIEVL EGDLEKSESA GKDEGDEADE
LDQLSVEELW KRMKNL
//
