ID A0A0V0ZL63_9BILA Unreviewed; 675 AA.
AC A0A0V0ZL63;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=DCC-interacting protein 13-alpha {ECO:0000313|EMBL:KRY13154.1};
DE Flags: Fragment;
GN Name=APPL1 {ECO:0000313|EMBL:KRY13154.1};
GN ORFNames=T12_9126 {ECO:0000313|EMBL:KRY13154.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY13154.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY13154.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY13154.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, ruffle
CC {ECO:0000256|ARBA:ARBA00004466}. Cytoplasmic vesicle, phagosome
CC {ECO:0000256|ARBA:ARBA00004262}. Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00004220}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004220}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY13154.1}.
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DR EMBL; JYDQ01000146; KRY13154.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0ZL63; -.
DR STRING; 990121.A0A0V0ZL63; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR CDD; cd13247; BAR-PH_APPL; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047181; DP13A/B.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR047236; PH_DP13A/B.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR46415; ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2; 1.
DR PANTHER; PTHR46415:SF2; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 348..448
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 536..669
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 451..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 181..211
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY13154.1"
SQ SEQUENCE 675 AA; 77825 MW; 35CE76949D086358 CRC64;
LELLGIRSKY LRPQPVFSKL FLLSLEFLVQ HCTPLTTFYL LYILKGQQHN NFLMHSIVPS
FVIAGQCISL IGVKIFNVKC YQKQTRCMLK VFEEDAKLLH EYVNQFQDQL ESLVAAQKQV
AQSMEKLSAF LGSYSRVCFP LALNDLEFPA LLEKFQGRIC ELGSWMNLMV QQLRNCVLYP
VNKLLSRLVE LENHKDEYDE LSDDLNTSLL KLVKLSPKCP AKKVEEIGTE YGLMRQRFHQ
AGLNYFTLLN LLQYQRRIAV VEPLLSLMYA YRSFFRMGNQ CMSHDEELDD FFTRVQEQIQ
SFHIEQQAYG QSTQDYMKTV EEIGRLQPDI YYAEGSPLDK FTAEKNPVRH KRGYLFFKSK
TALLTKWDRI YFYTENRNLV SQGRDDIASQ ILLEIDNTVH ASFADHEERR YCFSIGCANA
EFKKQFIFQA ICEKDCREWI EAINYISQHG NESPYRESLS TVENTSPPTE PTPDNNSTSE
RAFGGKYDNS SVISFGATTT TPIQFDMLNW SDEEELPTDT TLLSSSEEEM QMMNTFEVKF
LGCMEVENDR RETTAHDAIR QVLQARMVHN IIRAVDMKML LAGKPADQLR LLHPDSGRLK
ARFAMVDLVY WTSHANNERV LAFTVRRRGR KEGGKNLFIC YVLESTGCEA ASEICDAIAE
SVKTALQSFP INTPS
//
