ID   A0A0V0ZYC6_9BILA        Unreviewed;      1429 AA.
AC   A0A0V0ZYC6;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=GTPase-activating protein and VPS9 domain-containing protein 1 {ECO:0000313|EMBL:KRY17541.1};
DE   Flags: Fragment;
GN   Name=GAPVD1 {ECO:0000313|EMBL:KRY17541.1};
GN   ORFNames=T12_5639 {ECO:0000313|EMBL:KRY17541.1};
OS   Trichinella patagoniensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY17541.1, ECO:0000313|Proteomes:UP000054783};
RN   [1] {ECO:0000313|EMBL:KRY17541.1, ECO:0000313|Proteomes:UP000054783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS2496 {ECO:0000313|EMBL:KRY17541.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY17541.1}.
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DR   EMBL; JYDQ01000060; KRY17541.1; -; Genomic_DNA.
DR   Proteomes; UP000054783; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR041545; DUF5601.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR045046; Vps9-like.
DR   PANTHER; PTHR23101:SF25; GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR   Pfam; PF18151; DUF5601; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054783}.
FT   DOMAIN          152..358
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          464..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          683..729
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          828..854
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          869..952
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1136..1157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        688..729
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        828..848
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        892..952
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1136..1153
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KRY17541.1"
SQ   SEQUENCE   1429 AA;  158603 MW;  D5DD8B99A3A4E6AB CRC64;
     LTMRYQNQLA DLCYRLRDEK LLVNADIDLI LRLNTEVEEQ ILELVKICWI HCHQHRTLSK
     LLQSHPDATV QNACSQLCQL ENAHFSDSKK QLANNETTIT EILRLLLNSS KLVATVLHFF
     ECVEPNLADE LCFTFFCSVY GSCQFVNDEK CLYAVLCDLM RLQFSHCEGE NLRRMLRRGS
     GAFCKMYRLA TGSLFSVSLF LASALYQPIM QLISQNEQLL EIDPTKAAMR FSATEKLANW
     GLEGSSQYKE NIANYRKIII QRLVLVSNNF IQSIRDSLHC FPVPLAWLLR QLHFFLSDCL
     KLTTSECDQI CTELIFSYII CPAIANPEAF GILSDTPVSS VARFNLMQVG QILQALAVCP
     WDRLDSKLND LYSQFDTNSV HMLYRAILSD TVSIPLHRSN LDDIYTMEVK LARRHAAFST
     DELNQLLNAL RQVVENSSAP AGLESCWQEL KQLLNSLPTT ILLPSMNNNN NNNNNNNNST
     IVQQQQQQQH RTPSKQLIDL TETISSSTSR STVQSSTTTR SRSCMKLTKP LATMSLMRSP
     SESNVQNVPL QHQQQQQSSS PPALFSSTTT TTAASLLSAP TGYPDVFLFA ISDPREPVGL
     FGEEKFLSMM RQMKYGREES SCNAKRTRFM LAVDSDSLGA NSDQLDEVAS DEQRSDCSSA
     GQLTDHADMS ALNDNFSDVD AVPMSANVSG RGSPSISGRD TPSSVPADQN DNAFEVSSQS
     PCGSGDMRQK TSCCSLPLPT LKANAMEERF GKFAMMPTRN RECHRDETHS MVSDSWSTDV
     LASDSEFGGD VQQSQLPLSS AWLPDIVPCP APQAPRLDLI SEKAQHLHTS ASVGDHSDTW
     SVEASDSDND PNQRLRDIEN DVFQSVSGVG ENSRHILKSP VSDDGDSVSE QGLPCAYQST
     KPVHRQSSGS SLYSEIPDEG SSCGAGPSSS SLSSGAYLQH HPKQQQQRTW KTVPVQELSS
     SFRPYFNATS SNSNQKSCPG VADGNYPSVC FRAGGDKVDE FDREEVSVVF HNESTAMLSS
     SSVVRTTPTA AAGFGNSSNN LRTNFATTVA KKLSPHVNRV IGLRGSSFSS PSIATTTTAT
     TATATTTTTT TMLTTNTDLA APFSSIAGRE GLFRGFRGLK PLRGRTPARN VTNKLLGNGE
     SAAGSSSVQG ESACDSADGA PFASRDYAAE TGDQILDKYR CMALRNDDEP GGPTTTTTTT
     PLEPLVQMDE DTARPYYDSN NLTECQAFVD LKRKLRLILS TVDVDTLPVV TFRLSQTCSS
     LQQVKEHDEL KQFLRVQLAE TLISERMSLC VQIEDALRTL SYFDSKGVRK LLKTMHEEHG
     RRSAYVNYVQ QSKLSLLQSK MFIKKLLNRI TREQKITIHS VVEFCVRFYL EQRFDSQIKA
     FVHEFQQLQL LDEKTHLLST FLSHIYSSLQ ADSLWNGILK FTFTFLFYN
//