ID A0A0V1D7A4_TRIBR Unreviewed; 1243 AA.
AC A0A0V1D7A4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 08-NOV-2023, entry version 23.
DE RecName: Full=Anion exchange protein {ECO:0000256|RuleBase:RU362035};
GN Name=SLC4A10 {ECO:0000313|EMBL:KRY56835.1};
GN ORFNames=T03_10460 {ECO:0000313|EMBL:KRY56835.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY56835.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY56835.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY56835.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004554}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362035}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362035}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993, ECO:0000256|RuleBase:RU362035}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY56835.1}.
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DR EMBL; JYDI01000038; KRY56835.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1D7A4; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR013769; Band3_cytoplasmic_dom.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR003024; Na/HCO3_transpt.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR NCBIfam; TIGR00834; ae; 1.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF36; ANION EXCHANGE PROTEIN; 1.
DR Pfam; PF07565; Band_3_cyto; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR PRINTS; PR01232; NAHCO3TRSPRT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU362035};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362035};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362035};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362035};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362035}.
FT TRANSMEM 535..554
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 561..581
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 623..644
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 651..671
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 755..778
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 799..820
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 871..890
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 911..928
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 972..991
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 1003..1024
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT DOMAIN 163..451
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 504..1049
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1199..1243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1243 AA; 140365 MW; 137355EF837E6BD6 CRC64;
MADKKGAAVN ETDDVVRDTK ADEQNISDKD QMERLRISST ENGEHWYRGI GRRSDIVWFG
TGIHLPYDND KAKEHIPLER RQRRRRPTLL VSKDSDRMTP VEEDRIVMAP SARVQQLLNQ
QKNGDNLEWQ PSHSLFTEME FLYGTGPNQE WRETARWVKY EEDVEEGGNR WSKPHVATLS
LHSLFELRSC LMNGVVILDV EATELETVIE HTISTLLSEG LLKQSAVNTV REALLSKHKH
QYEQNKAHKE GMSSGQSFLQ TVRSIADIGR SLSHAKSMTP TVVESSAVSQ IPAPVSPTAL
NVPDTGLNKL SGTALSAAKQ GSRVMDGSDI TAKGNYHLYK KLPRGAEASN VLVGQLSSLD
NYISAFIRLN KACHFNNLTE VPVPTRFMFI LLGPEGHKLK YREIGRAIST LMSDEVFCDV
AYQARNREDL LDGIDEFLEQ VIVLPPGEWD PKIRIEPPTS VPSQEARKKL VPKKEDAHGS
LNNNIDEDIS GGHGQDIALK RTHKLFGGLM ADIKRKIPWY ASDFKDAFNL QCVAAFLYMY
FAMLAPIVTF GGLLEEATDR NLAAIENLFS GAICGTLYSL FAGQPLTMIG STGPVLIFER
VVFDLCKKAS LDFLSVRFWI NTWSGVILVI IVAFDASAMV SYITRFTEES FSALISFIFI
YESIAKLIKI LQNARIIKWN PLSATGVGGN CSCSGKPVES AFMDDVKSMI SRRRMNASSW
LFHQPDENIS YIDWDNVPLE HCEYLNGQLT GDSCYYMLDV FLMSLVLLAG TFTIAMVLKR
GRNSSYFPTS VSTIETVRTI LSDFAVFIAI SLMILLDYFV GLQTPKLYVP ENFSKFLKRN
VPYLQLIHVN LFQPTLESRG WIVHPLPDPS TWWIIPLGIA PAVLLCILLF MDHQITVVIV
NRKENKLKKG CGYHLDLLLI ATVCFITAFM GLPIFVAATV MSVSHVNALR VESECRAPGE
KPKFIGVREQ RVTGTLVFLF IGFSTLMTSI LKHIPMPVLY GVFLYMGVSS LSGVQMVDRL
LLLFMPMKYQ PDYIYLRHVP IRRVHLFTFF QITCFIIMCV VKEVEVTSVA FPLMLVVLVA
IRKLLEYVFT EKELKLLDDQ MPEITLRKRE DAKKKRQKEQ QEEQQNTLVP VQTTSNLHIP
LTSGHVMSIP LESLNPEEKV NLSEEVNRSG LWKHIASYSD MTKNMKKMKI NDQKELKTFA
EEEDDSEAIT ISFDRAEETP STEKKPLLND AEPPNENDEM SRM
//
