ID   A0A0V1D8X9_TRIBR        Unreviewed;       429 AA.
AC   A0A0V1D8X9;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Fragile X mental retardation syndrome-related protein 1 {ECO:0000313|EMBL:KRY58061.1};
GN   Name=Fmr1 {ECO:0000313|EMBL:KRY58061.1};
GN   ORFNames=T03_13742 {ECO:0000313|EMBL:KRY58061.1};
OS   Trichinella britovi (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY58061.1, ECO:0000313|Proteomes:UP000054653};
RN   [1] {ECO:0000313|EMBL:KRY58061.1, ECO:0000313|Proteomes:UP000054653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS120 {ECO:0000313|EMBL:KRY58061.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY58061.1}.
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DR   EMBL; JYDI01000024; KRY58061.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1D8X9; -.
DR   Proteomes; UP000054653; Unassembled WGS sequence.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0006417; P:regulation of translation; IEA:InterPro.
DR   Gene3D; 2.30.30.140; -; 2.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR   InterPro; IPR040148; FMR1.
DR   InterPro; IPR040472; FMRP_KH0.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   PANTHER; PTHR10603; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN; 1.
DR   PANTHER; PTHR10603:SF7; SYNAPTIC FUNCTIONAL REGULATOR FMR1; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   Pfam; PF17904; KH_9; 1.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR   PROSITE; PS50084; KH_TYPE_1; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT   DOMAIN          100..145
FT                   /note="Synaptic functional regulator FMRP KH0"
FT                   /evidence="ECO:0000259|Pfam:PF17904"
FT   DOMAIN          222..254
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|Pfam:PF00013"
FT   REGION          295..409
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        355..382
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   429 AA;  48350 MW;  F79D26228C6A9EB0 CRC64;
     MDIEVKGEND CYYKGTIQAL HSNGAQVVLE NEPNTPKLYQ YEYLRLSPAD TSAKPITFTE
     GQIVEVFVCP NEVEPLGWYQ AKVHSIKGDF VCVDINAPVS SKEVISVDLS CYDDAIERAE
     MLAEMHFRLL SQKLSLKQRT EDATKQLQDG IVEQFVVPHY LMGLAIGGHG SNIAQARAVD
     GVIDVKITPA GDDMVEFRVI ANNAKAARKA RSLLEYSEEP YMVPRDMVGK LIGKSGLAIQ
     EIVDKSGVVR VKVPFWYIGT VESIKNARFL MSYHMNHLKE MESLRQEAQE LNRQLRGRMT
     PPHNNYSNNQ SRSERAYHSD IESNPPVRGR GGYGRPRGRY MRGAPPNSGG DGDMMYQARE
     RRRQVDEESN PAPEHPEDRD SASSQEAGTN MGIRRNRRRR EGRVHRWTGG RGSGVYIYVS
     NFNLTAVFH
//