ID A0A0V1DDS9_TRIBR Unreviewed; 2362 AA.
AC A0A0V1DDS9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Filamin-A {ECO:0000313|EMBL:KRY59626.1};
DE Flags: Fragment;
GN Name=cher {ECO:0000313|EMBL:KRY59626.1};
GN ORFNames=T03_10861 {ECO:0000313|EMBL:KRY59626.1};
OS Trichinella britovi (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY59626.1, ECO:0000313|Proteomes:UP000054653};
RN [1] {ECO:0000313|EMBL:KRY59626.1, ECO:0000313|Proteomes:UP000054653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS120 {ECO:0000313|EMBL:KRY59626.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY59626.1}.
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DR EMBL; JYDI01000011; KRY59626.1; -; Genomic_DNA.
DR STRING; 45882.A0A0V1DDS9; -.
DR Proteomes; UP000054653; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd21230; CH_FLN_rpt2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 19.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537:SF18; FILAMIN-A; 1.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00630; Filamin; 16.
DR SMART; SM00033; CH; 2.
DR SMART; SM00557; IG_FLMN; 19.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF81296; E set domains; 19.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50194; FILAMIN_REPEAT; 20.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 68..174
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 197..300
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REPEAT 324..422
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 430..520
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 520..559
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 687..738
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 747..838
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 839..935
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 936..1033
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1034..1126
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1127..1225
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1226..1321
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1323..1418
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1448..1522
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1522..1621
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1618..1707
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1710..1802
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1827..1900
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1903..2020
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2022..2140
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2143..2234
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2268..2362
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY59626.1"
SQ SEQUENCE 2362 AA; 259019 MW; 19348CF00FCCCE30 CRC64;
LSTGGRRQTI KANRPNLQEE AHNKAASHTV DLAIIRMIFA LCQQSITSCR LVEVRGSIQS
RDKAKWKTIQ QNTFTRWVNE RLKMVDCSVN NLETDLTDGL LLIRLLEVLS KKKLPRYNKK
PNFRSQRLEN VSVALSFLET VERIKLVNID SSDIVDGRLK LILGLVWTLI LHYSIDAQIW
DNEKNLQNQE NKHKPPIPPK QRLLDWLNSK IPGFHLTNLT TQWSDGRPLG ALVDSLAPGL
CPEWSMWKAA NALKNTTIAM DLAEKWLVIP KLIEPEEFIN PDVDEMSMMT YLSQYPNAKL
QPGAPTGSSV VGKTDSNNFE YPVTKAKQIL QIKASGPGLQ SGVTCGKTTH FDIYMAGGDE
KKFAIQILNP NGKSDSVNQR FRRLSGDMLR CEYTPDMVGM HTINIFYDDH SVLNNNPYEV
WVASESFEWK VFGRGIQNSG IRVGDKVDVR ILCNGDANAS LVEMIVKHSD GSIVPIHRKN
TSIRPLKVEG IYQPIQAGLH IVQIKYDGKD FPSSPFEVMV DSEMTSKIRA FGPGLQSGVV
NRPCKFTVET NGERCGLGKN LPVKHKQWGH ADAGLNVVCV CERCLSQICW HRSSVLEFCL
RRIRQSRQTT NPKHEAVSIT VPPTNSTPPK LFNSGNASCN IPASAASWQT EARFSLERRP
EGMDMKWKCS ISTINNELCH CNYRRFSVDG PSKAELTCHD NGDGSAEICY IPKACGEYAI
HVLTNDVNIS GSPYMVEIGE SHLGCIPELV KCSGAGISEY GHVCGQRSTF TVDASRAGDS
AVKIFAMDSD GMEMNIQQKT IANNVYSCSF VPESCKRHWI MVTFDDQSVP GSPFKIHVSE
QTNPNLVRMY GPGLEESVRT KDRNHFFVDC ADAGPGKVEV CMKNHADGSP VDVQISDCGN
GSYTVYYKVN KPGQYDIYVR FAGSPIPGMP YKVQVKPHVD LSSVVIRGLE ERVFINSISE
FTVDTTALTK KISNAEVSCT IRSPDGNMAR CRVKNEKDGT YRIFYSTIVE GKHELQVSYD
DVPLTAQPLL VHAVDGHDET RCKVQGAGLK AGMVGIPCRF RVDTKGAGSG KLNIAIEGPS
ESTISTANNL DGSCTVEYVV SKAGVYKISV AFAEKHIPGS PFTALIEPLL DPNLVRAWGP
GLESKNCRFD LPLHFLVDTT RSGPAQLQVL VDSECGAAPK QPEIVEQAHG VYKVTYYAPE
VDSNCKVHIL YGGKEISNSP YCMRVLPKCE AKKVKVRGCG LENFYYVSDP VTLSVDISEA
GYGALQMMIK DPEGLLVSTK HTEKGTYLDK FTFIPDIAGT YDISIKYGDE PVLNSPFALR
VLPVGGDFSK CQITEGRFET ATVGEEQCIK VSTDPAGRGR VTCQILSAEP PTKIVNVVIE
QHDDFCLLFY TLPNPGLYRI TVRYGGQILQ KGQWFIRGEL SRRGSVGETL IATPVVVSRG
IAEDNSAEAE FSEKSWTFAL PGTGRLTAKV VMPSKKTDTP IIRDNADGSV SVKYQPSEVG
LHELQIKHDG LHVPGSPFSF HVGQVDDGYV TAYGNGLSFG IAGEPAQFTV CAREPRGGSS
ILASGGLSVK IEGPAKADVK CHDNKDGTCS ITWIPPAPGE YTVHIQYAGK TIEGSPFKAT
VSGEGRKRAQ ISVGSTSEVS IKVTDPDVSV LSASIKSPSG IEEPCLTRKL DSGNLGVSFT
PREPGEHLVT VKKRGKLIHG SPFRITVNKA DVGDASKVKV TGAGTSQAIT QEFNSFQLDT
RQAGYGGVSV SLEGPSRCEI KYEDNKDKTC KIFYKPFEPG LYVLNVKFAD HHVPGSPFTL
HCEGKGVGTV TETIEQTIPA SPCVMPGDDC HVSLKIPGSS AIDLTASVMN PEGVIEDVEL
CEDSEEIYLI RFTPQMLGVH TLSVLRHGQH IAGSPFQYTV GPFQDSGTHK VHAGGPGLIS
GEVNMPCFFS IYSREAGAGT LQIYIEGPSK AKLEYHEYRT GDGYISYCVT KPGDSSYRFL
LLLELFSRTA MLWFFCSGDY NVAIKFNEKH IPDSPFKVYI SSPTGEARKL EVCSFPDSYG
LAVNKPVTFT LVTHGAEGNL DAKVFSPSGA TDDCFITPIE EHGKKYFSVA YFFNSQNICI
VLYNTESYAI RFVPKEIGNH YLHITLDGIH MKDSPFRFRA GPKGEVDPIG VTVIGEGLRS
GITGHKCEFT INTCHVGPGN LQIQLDGPSK ATLDAYDVEI GYKVRYTPLA PGDYFVTIKY
NGIHIPGSPF KINVTGQHLG GSGINESSKV NINTVSKSSE GAAMQVPKYY SDASLVVCQG
AGLKKAFASR QNIFNVDCSR AGQDLLFVCV MTQKGPAEEM HIKHVGRGVF HINYMVRERG
TCFVHVLYGN KHVPGSPFML QI
//
