ID   A0A0V1DHK1_TRIBR        Unreviewed;      1742 AA.
AC   A0A0V1DHK1;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Abnormal spindle-like microcephaly-associated protein {ECO:0000313|EMBL:KRY60626.1};
GN   Name=ASPM {ECO:0000313|EMBL:KRY60626.1};
GN   ORFNames=T03_5188 {ECO:0000313|EMBL:KRY60626.1};
OS   Trichinella britovi (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY60626.1, ECO:0000313|Proteomes:UP000054653};
RN   [1] {ECO:0000313|EMBL:KRY60626.1, ECO:0000313|Proteomes:UP000054653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS120 {ECO:0000313|EMBL:KRY60626.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY60626.1}.
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DR   EMBL; JYDI01000005; KRY60626.1; -; Genomic_DNA.
DR   STRING; 45882.A0A0V1DHK1; -.
DR   Proteomes; UP000054653; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0043226; C:organelle; IEA:UniProt.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   CDD; cd21223; CH_ASPM_rpt1; 1.
DR   CDD; cd21224; CH_ASPM_rpt2; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR031549; ASH.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR   PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR   Pfam; PF15780; ASH; 1.
DR   Pfam; PF00307; CH; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   PROSITE; PS50021; CH; 1.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054653}.
FT   DOMAIN          417..548
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          1335..1375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1568..1595
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1344..1367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1742 AA;  197136 MW;  EBF120520E2B235F CRC64;
     MASYALYSPS QSPVRLELTH FSRTAVLSFG SVTFGKTAQQ SFLVVNNKQC DQQFFFDFSS
     VNRTDISVDN EAALVPAKGE IECVVKWKPT ETGNFRISLP LKVTMFPSDE DEYLDAPIRY
     WLRATLVGSC VLPQEILLKQ KKVPLCIQRI PMTSAIKSNV KMGREFESEK LSARPNRIQA
     NHNSQQSVRK DANFKHPFVE HVFTTFLNHL LTQDFITDDS NSEATQVNLK KIFSSSSANV
     SPKAAAQRRV SLKQYAAVQQ LNLLRLSASK AFCEVRAVVY RVCQAVEKGK ILVRREVAIH
     RDQGIMRLIT NLLLSVHPLW LRIGLEVVYS EIIQLDGDCT VRGLISFIRF RMLSDPELLK
     QYGIAHVRSI YKNDYQPAIS KFFLQKFLSL FIFLDFAKQK RLIKQDPCLF NPNSKYKTIR
     DIFVVLNKEI LSGEGNLFKT LAAVGYVPKY KQAWYDEKPL AIENLAVDLR DGLALTRLAA
     MFTENPGLVT NLRGPPISRL QKLHNVQLAL DNFMSANINI GDVDAASIVG GDRDKIMALL
     WRLILHKVGL EFPDEVVQSP LMPEIISLRR SLRMKNSPEA KKMLNIKLHK KMTISELFIC
     WLGCIAAHYG IEVDNLNLSL ADGRVLCCTI NYYLPSVLPV DVIKFETSMT TSRESFIPPN
     ELKSNEKANH MLFQKSIREI GHVPDFFEFD RLQNLEYTDE RVWILCLNSL ATVLFALRRE
     QQAACIIQKA WKTYLRKNCQ QAVETHEYSN VDHFNEHLLV QNEQLKIEEK ENFIVGEMPF
     DEKEQGETCA VAVVDENDKM ESGDNLSMEI ETLIEFQACC RRKLVLNNFL QQYKSDSGNE
     YERSDEEECA KELSNAQSDQ NADAFDCMTR SEVVQQQNHV YGINVKSNSS LLDANERKVE
     NSYAVHDAKD ELSLFENNII NLNRNQSVIA NESVCLLETN VAAHKQNELM EPTLGDQKPE
     FLSSSSFLSN LSDMQNALPA VDEVKSISLA DIPRIVIEEC RSPAETTASI LSSTTSALKS
     SGSNGKGFAE LDAVNEAECP APFLLIEKLP KFSEMLEMFE FRPLEEKRYS PLNFDERQQP
     LYRSTKVLSL STENFECFSD DSGQNLTALL CSDGASSADV RRETNITVSS ENLLNMQMSC
     NCNYGQTDQT EADLKPSNDE TIAFNEPGNV GAGTDGTDLC MGPTELLFCS DRCDQNFIPL
     KTDKSVSLME AVDNLKHLTE IPRESFPANQ TSMNNMAEDC LSPPQFGSLT KTPQFDSTIV
     GENAAEVNVE FPNLTSAKSP QHQAEYTSLI ASFLQSEKMR ESAVNFNERL EYSPIPSYLK
     SSKLHAKCTA PEFATEDADA TVQVEPTARS SEYGSSPENS EKKLNNTESS NLSDKDSEDF
     VIKEVRDYFE TPSLRSIRSA IEVDSKFQMT PYIAECERLA NRNDSLSFNF LKFSSIDFET
     PIQNRLHNSS SNYSGRPTLT ASILNASTRN IFEEIMSAEA KEKNKSNGII RRIPCLTLQQ
     NVMDSIIEQE NCLDTELPVL QNDTLLHKNT NSVQFHFLNA MKKNVVTQHD EISNLLKTIV
     ESDRLVCIEN AVLRLNELSK ESEDMCKRMV ELDAAEKLLA LVNRLNRSFN SSIIIDIVMK
     CLKQITSHQS TMKSVTESVD WFQSLAWQLI YFKDTKPSDT FCNIVAIFCQ LSVLDVAQAA
     FQENLQFVAR FERIRKHISK RHEWLVKKYE SVSSDLSENL PLKDSAQRLE ALKALYSCYE
     LL
//