ID A0A0V1H0A9_9BILA Unreviewed; 622 AA.
AC A0A0V1H0A9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Diacylglycerol kinase {ECO:0000256|RuleBase:RU361128};
DE Short=DAG kinase {ECO:0000256|RuleBase:RU361128};
DE EC=2.7.1.107 {ECO:0000256|RuleBase:RU361128};
DE Flags: Fragment;
GN Name=dgk-5 {ECO:0000313|EMBL:KRZ03954.1};
GN ORFNames=T11_14772 {ECO:0000313|EMBL:KRZ03954.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ03954.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ03954.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ03954.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-
CC phosphate + ADP + H(+); Xref=Rhea:RHEA:10272, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17815, ChEBI:CHEBI:30616, ChEBI:CHEBI:58608,
CC ChEBI:CHEBI:456216; EC=2.7.1.107;
CC Evidence={ECO:0000256|ARBA:ARBA00001383,
CC ECO:0000256|RuleBase:RU361128};
CC -!- SIMILARITY: Belongs to the eukaryotic diacylglycerol kinase family.
CC {ECO:0000256|ARBA:ARBA00009280, ECO:0000256|RuleBase:RU361128}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ03954.1}.
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DR EMBL; JYDP01000177; KRZ03953.1; -; Genomic_DNA.
DR EMBL; JYDP01000177; KRZ03954.1; -; Genomic_DNA.
DR EMBL; JYDP01000177; KRZ03955.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1H0A9; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007205; P:protein kinase C-activating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF114; EYE-SPECIFIC DIACYLGLYCEROL KINASE; 1.
DR Pfam; PF00609; DAGK_acc; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR SMART; SM00045; DAGKa; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU361128};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU361128};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU361128};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361128};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 81..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..232
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ03954.1"
SQ SEQUENCE 622 AA; 69554 MW; D8355F071E2EFBB6 CRC64;
LCFQEVIVIM CSWCKVSYHN KAKCFNTDLI EQTCDFGALK DIIIPPTWIN KIPTSRCSTY
RRVVLSNASV RRRKRNRKER IFFVNPLQST VNMPAFPLLI FVNAKSGGKK GKKLFRDLCW
LVNPRQVFEL SYGKSPRFAL DMYRKCLPQL RILVCGGDGT VSWVFSSLDA MKIPSSRYPP
IGIIPLGTGN DLSQTMGWGS TYFDDSIAEI LPSVMQDTVS VKFDRWYIDV APNPTSEQSK
DTENAIDSLP VNVMNNYFSI GVDAHIALQF HESRAAKPEI HKSRFKNRLV YGSIGTKDLF
KRAWKDLSEY ISLECDGIDH TNRIKELGLH CLLILNIPKY AGGTMPWGNQ ASSLVTLGIW
AVNNSMPIPK ISSPSYEDGR VEVVGFTAAS LAALQVGGRG VRIAQCSYLR LTTKKVIPVQ
VDGEPCKLSP SIITISLFCK VPMLKRISHK DNEQLNSLGL RPEYAVTRAC AVTICDEMAK
CTSKVNVAFI PWTEYEQLKC TPSELSRHAT VVGEIEADYD NDLEHLRPLV DSILQSSTSA
LLSNTTNEEW YYLDCSNSDE VFHIDRSYEA FTSVTEICEK NGSPLVIVGY VSSNSVASVP
DELLNPLQKR FQEISVASVP SN
//
