ID   A0A0V1HDZ7_9BILA        Unreviewed;       567 AA.
AC   A0A0V1HDZ7;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=TWiK family of potassium channels protein 7 {ECO:0000313|EMBL:KRZ08448.1};
DE   Flags: Fragment;
GN   Name=twk-7 {ECO:0000313|EMBL:KRZ08448.1};
GN   ORFNames=T11_14308 {ECO:0000313|EMBL:KRZ08448.1};
OS   Trichinella zimbabwensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ08448.1, ECO:0000313|Proteomes:UP000055024};
RN   [1] {ECO:0000313|EMBL:KRZ08448.1, ECO:0000313|Proteomes:UP000055024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ08448.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC       1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC       ECO:0000256|RuleBase:RU003857}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ08448.1}.
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DR   EMBL; JYDP01000086; KRZ08448.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1HDZ7; -.
DR   STRING; 268475.A0A0V1HDZ7; -.
DR   Proteomes; UP000055024; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   InterPro; IPR003280; 2pore_dom_K_chnl.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR   PANTHER; PTHR11003:SF98; TWIK FAMILY OF POTASSIUM CHANNELS; 1.
DR   Pfam; PF07885; Ion_trans_2; 2.
DR   PRINTS; PR01333; 2POREKCHANEL.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003857, ECO:0000313|EMBL:KRZ08448.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003857};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003857};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT   TRANSMEM        91..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        224..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        304..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        337..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          191..249
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
FT   DOMAIN          314..383
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KRZ08448.1"
SQ   SEQUENCE   567 AA;  63833 MW;  9D368A9B3B06E060 CRC64;
     SFCIYVCFII TGCKRRNAIA IRIKWHIKTD HLKSAVVMLS KSGAMLKSHA YQDQSRSNEE
     GQSLIGMEMN PVDEDDEVSC GKRCGRILKI ALPHVGLVAL LTIYTVCGGG IFHLIELSHE
     LQVRSNSLKL ISQTKTRFLE NMWNLSQAEG MTSEQWQMQA MDSIKSLEIV LYEAYEEQYI
     TINDILNKTH RTIWTFPQAI FFATTVITTI GYGNMVPKTV SGRVLCIVFG IFGIPLLLIT
     IADIGKFLSD LITFLYRQFR TLKAKLGKHS RNFTFCGKKI SINEDAKDSE LDNISEQTSE
     SGDVHLPVVM AMVVLISYTA FGGLLFQMLE GWGYFEAFYF CFITMATIGF GDIVPSEQVY
     LFFTIIYIVV GLALTTMCID LAGSEYITKL HYFGQKIETA RDAFGGAVVS GLHAGEQIFK
     HSAFIRTAGG RLIQISDAML LNTKQATALR QKYGLPDDYD FSVVSSPLIT DDGTLITNNM
     LFAPVSPEVL KVAKTHIKIR PEEIRESDAF VLQNRTFNRP FDGGLYKRGS VRSSRSLGKR
     SRKRQWLKQD KYKFFLIAPF ILKESCV
//