ID A0A0V1HT68_9BILA Unreviewed; 1060 AA.
AC A0A0V1HT68;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 30.
DE SubName: Full=WW domain-containing protein {ECO:0000313|EMBL:KRZ13788.1};
GN Name=tag-325 {ECO:0000313|EMBL:KRZ13788.1};
GN ORFNames=T11_5466 {ECO:0000313|EMBL:KRZ13788.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ13788.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ13788.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ13788.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ13788.1}.
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DR EMBL; JYDP01000029; KRZ13788.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1HT68; -.
DR STRING; 268475.A0A0V1HT68; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd13233; PH_ARHGAP9-like; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 48..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 441..474
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 629..729
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 832..1056
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 347..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 994..1023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1060 AA; 119304 MW; E46E4D2D0B073DAA CRC64;
MFFGIRVLSL HVASKELKKA FPPTRRCSVY TQDGIHWLPL YRFKWMPIIA SISRIKLAQT
VLSVIFVPVA YSAYQEKQIS LNQLYVLVFI CVFALFMLFV MSGIFRRLIG VVSLDESRNV
IRIGHLTFWG ARRNVEIPLE DLTPLSEVNF RPGDVYAAIR RYSDSKMCLS LVEVLYNYDS
TTSRGHRVHV LAGEKFYLVS DADEHWWFVC KDWSNIDGFY LPKSYLRVLS VQSGILSSDQ
TPAVISDDDD DDDDVCGGVS KDEMIRTSVA NGHRPFVVAE EEPEVEVEES LPAHRWPAVL
ANGKAGKLSS ARLVSASIPV GLEMYCLERA DQRSAHLNGD HGLVGVETSS SSGRCSTMGT
VGAQSRSLDN DLPMSSTCSS STGSRNHSNN SSSSSVVIAL DSVSVSDALV NARSRSPIYA
NIEECTDMSI PAITPDMQPI RTLSNGWQEY ISESGRPFFY HPLIEIASWK PPRSSTSTTN
QQQSNVASST RAMLDSSSSV LDNLSMFDKA KSDHCKRSKS KLTDVDVEPQ QQQQQQQQQQ
HKQQVQRSGF SIDEEADDGR GEHCVRVSIR DFSDLNRLLS TSQQHPATRP TSTSLYGQCM
SASDGALKFS AFHSSTGTVI KCGNLNRCKV MEAGKRIRKH WSTCFVYLTN AHMIFYKDKK
SSEKQGNQYC APLGVCDLHG AKIKWLVDDK NKRKRLFQLE LVDGTAYLFH TEVDNEIVDW
YDALQKIVNE LPNPGFQRTP VIERSSYKTS SRRVCTTTGQ KIAKDAKNLH DQKEKQSTSR
GINNGPTSDS VEASVPSKQS ILEKLVRFFR NRPSVEFLKE RGIYKPEPVF GSSLTEICRR
EKNTVPKFVT VCMSLIEERG LETDGLYRMS GNLSQIQKIR CSVDQEKYNV LMNENDIHVL
TGTLKLFFRE LQEPLFPPFL MKEFMNAIKL QNAKMRYCAF RDLVARLPPP HHDTLDALLV
HLLKVAEKSS TNRMQIHNLA IVFGPTLFSS CPKPDKVESG GQRRKKMMMK KSASKYSEPS
TSGHVDVIQS NSHLAFSMIM HGQIVEYMLK EHSKLFKVKV
//
