ID A0A0V1I6E3_9BILA Unreviewed; 705 AA.
AC A0A0V1I6E3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
DE Flags: Fragment;
GN Name=mog-4 {ECO:0000313|EMBL:KRZ18392.1};
GN ORFNames=T11_6506 {ECO:0000313|EMBL:KRZ18392.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ18392.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ18392.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ18392.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ18392.1}.
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DR EMBL; JYDP01000003; KRZ18390.1; -; Genomic_DNA.
DR EMBL; JYDP01000003; KRZ18392.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1I6E3; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0022414; P:reproductive process; IEA:UniProt.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:KRZ18392.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..705
FT /note="RNA helicase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011869512"
FT DOMAIN 70..234
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 259..433
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ18392.1"
SQ SEQUENCE 705 AA; 80675 MW; F02BE5DB5D13F39F CRC64;
LHIIIIIFFI KMAQDFSLVL EDTVDFVKAL QLPGTDEKEN AEELARLKQR QSVEETRRSL
PVYPFREDLL KAIEDHQVLI IEGETGSGKT TQIPQYLYEA GYCKDGKKVA CTQPRRVAAM
SVAARVATEM NVKLGLQVGY SIRFEDCTSE KTVIKYMTDG MLLREFLSEP DMQSYSVVII
DEAHERTLHT DILFGLVKDI ARFRTDMKLM ISSATLDAEK FSSFFDDAPI FRIPGRRFPV
DIYYTKAPEA DYIDACIISI LQIHLTQPLP GDILVFLTGQ EEIDTILEAL QERCRQIGTK
MKELVVVPIY ANLPSDLQAK IFEPTPPGAR KVVLATNIAE TSVTIDGICY VIDPGFCKQN
SYDFRRGMEF LHVVPISKAS ANQRAGRAGR TGPGKCFRLY TAWAYQKELE DQPVPEIQRT
NLGNVVLMLK SLGIHDLIHF DFLDPPPQEA LVLALEQLYA LGALNHRGEL TKLGRRMAEF
PCDPMMSKML MASEKYHCTE EILTICGMLS VNAAIFYRPK DKIVHADTAR QSFWVPGGDH
LTLLNVYNQW KDTDYSIQWC FENFIQHRSM KRARDVRDQL EGLVNRVEIE VESNPTDTVA
IRKAITAGYF YHTARMSKSG HYQTVKNHNT VYIHPNSSLF EDRPRWVLYH ELVFTSKEFM
REIIEIENTW LLEVAPHYYK QREVDDTTNK KLPKIVGKTG EELRR
//
