ID A0A0V1KXD8_9BILA Unreviewed; 1989 AA.
AC A0A0V1KXD8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Pappalysin-1 {ECO:0000313|EMBL:KRZ51685.1};
GN Name=Pappa {ECO:0000313|EMBL:KRZ51685.1};
GN ORFNames=T02_2030 {ECO:0000313|EMBL:KRZ51685.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ51685.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ51685.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ51685.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ51685.1}.
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DR EMBL; JYDW01000217; KRZ51685.1; -; Genomic_DNA.
DR STRING; 6335.A0A0V1KXD8; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR000800; Notch_dom.
DR InterPro; IPR043543; PAPPA/PAPPA2.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR46130; LAMGL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46130:SF3; SUSHI DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF00066; Notch; 1.
DR SMART; SM00032; CCP; 4.
DR SMART; SM00560; LamGL; 1.
DR SMART; SM00004; NL; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 1448..1506
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 1825..1844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ51685.1"
SQ SEQUENCE 1989 AA; 222426 MW; 0F5CE287E6287D74 CRC64;
LGNLCSCCGL FVICIRLEVK DGSLVVDQVS RFRDEGSSSC ILTDRLDFIQ SQERKLVLFL
ERWATGDWKR ERSAAVESDI SNLNTSNGPL DSGWVWGMRR RLYIKGSNLS SRFDSRNYKK
QSRRRVCRFL VFSSSALAAS ASICSYSYSY FAAAATTTTT TTTTTTTTTT TTTTTTTTAT
TYSSFAYSSI VFCISAMHHL LLLFTLCLAC LTNAVDDTTL ANCAVGTGTR LDHRYHPNVR
HPRSVSNGGS YSTTAKAIYF DGQERTVRLQ DVGQLPRDQF TLTVWIRPEG GQGDPAIIAE
LADGCSGDDD DDDGPPFVWQ LGIATKTASR EKGAHFFFQM RNEMSSSATV LWSHYPYKAE
RWVHLAVTYD GIMLRFFVGG ALVATTDKQI GPLFSNIKSA CKHLLLGGPM PGRFDEGHTM
NFRGAVDELQ LWSTFQEYNF IQKMATGRNA QEAADNNNHN GQHPTTTSVL IINAQSVAKW
KPAGDFAPKF VPSDLDAFFN TYQLLVHACG QTVCDHPDVV RSYSANWELR QSKVVRYKVI
NIVDNSTGKG IVSDRKIELQ HGSLSGAFAK YNITWQMEIV KIANANLRKK KIIFGCDSSK
IGNKQCDLEC RHPITGNDGG DCDELMLVRC QRRMLGNGRC DPECNFPEYS WDQGECCNKT
LTDVTTNCID PQSPFRPYIG IEEYKRMLNV SNEDALTISF VEWSNGDLIG LSTFPWEKHV
FSIYGGIVVQ PKRFGSDGHR NNLIHEFGHA LGLWHVHHGI SEMTCDDPCR ETKPSLYTGD
LCEDTNPTPK NVECKDPEYV SFDSRQSMAE LSGCESGSQM YLNTPYDNYM SYSDGECATH
FTPQQVARMH CYLDLKYSSW MASSESLREY VPTAPRILRK TETSLTFAWL PPLSWHQCKP
AVERCQHCEC DTDGRFIQYA SRVIANHTAR TTSYWSPDQA LGPPDAEPCE ASTKSWLPDA
QNCDNNNACS LVLGFEVAVV PAHLKLWISW NAADGLKHFI LHFDDSSMIA LPPATAFCDM
PYTLSLDTDK RLTKVELTTS SPFVSIDAVQ IVSNPNHELC SKCSHIDYNI VREPPFPKPP
LVQSTADTFF TDRDLKQDQV YMYRIGARRT NSNGAVYFSP PLIYSHSWSF CGDGNLDEIA
YVFVLARLCS LVWRSPSFCY SLDGVQHAHA INGSPIMMSD MPDVSYASEH SDQWAARAFS
NAEPINLRCN TTMILGPPRN LVCQVNSPPG LSWQPCLPSV MKNVWIEVEF EQPVVATAVF
VHLASDGYAG VDSEYRFLRL ELVSVDNKYY ELQNSKLVTV SCAKSPLEYP VWHDLTKPFF
YSRAVRIHLS SERISIAAVR LRSKRNFDPV VLELCSKSDM LYSVFANQCV SSQCSVVSCK
SVIVNHADVQ CTGHSNGDSC IVTCMKGYHL VKHERAQTHA FSYSSQRSAK IICLNGQWSV
GNLKCEPVDC GWPKIFRAEV LCPDGTRLGA KCSFRCLRPA IMQGTKREIT CGERGAWSVP
EAYCQLSCGP SLEGELNGRA VSKLCRINFL TLDLKSVGYP VGTKCRIVCK AGYHVEGHSI
NKSQSYLNEA VNLNVSGYYS INQQAGRVFK RVCDRNGHWK GHRCVKIKCP EPAVVYRGLY
NCTKGFEVGS QCSFYCPFSS QIRDSICMMD GTWSIADPCV LPKDVTCSIP HAPGHIVVSC
PSKRLVGSTC HVACDAQGYD PVVEHVVNSD RNFKMHVLQK ITKLTCSIKR KWEPEVESLI
CVKRCTQDFV GDGWCDFQNN RAYCGWDGGD CCASTAKGGK VKLMFPLLCT SHLCRCLDPY
AVENRNPRII PRAFLVQGYH GGEALDKEEE EEEEDLDENN STEHIQSPDL MMMLMNNDKN
RTNPSWKPLG LGSRVKFAWE TSGGGFSTAK LDHLSSSMLV LFLQALKNVS SDPRDPFLLL
QNSATTNATI KRLKELDAMT RFLKRPTAST AQPLTWTTRW FRRRVVHPQL STSILKALRK
QHESLQVKS
//
