ID   A0A0V1KZB9_9BILA        Unreviewed;      1366 AA.
AC   A0A0V1KZB9;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Transient receptor potential cation channel trpm {ECO:0000313|EMBL:KRZ52380.1};
GN   Name=Trpm7 {ECO:0000313|EMBL:KRZ52380.1};
GN   ORFNames=T02_11394 {ECO:0000313|EMBL:KRZ52380.1};
OS   Trichinella nativa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ52380.1, ECO:0000313|Proteomes:UP000054721};
RN   [1] {ECO:0000313|EMBL:KRZ52380.1, ECO:0000313|Proteomes:UP000054721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS10 {ECO:0000313|EMBL:KRZ52380.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRZ52380.1}.
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DR   EMBL; JYDW01000195; KRZ52380.1; -; Genomic_DNA.
DR   Proteomes; UP000054721; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR041491; TRPM_SLOG.
DR   PANTHER; PTHR13800:SF1; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL TRPM; 1.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF18139; LSDAT_euk; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KRZ52380.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        885..905
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        956..973
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        982..1003
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1015..1036
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1095..1123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1143..1162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          95..357
FT                   /note="TRPM SLOG"
FT                   /evidence="ECO:0000259|Pfam:PF18139"
FT   DOMAIN          888..1119
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          532..555
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1261..1305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1318..1366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1214..1248
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1261..1302
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1343..1357
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1366 AA;  156325 MW;  6E31586B38293B67 CRC64;
     MISRRQKAAN QVNEWIRERF LKRECFKILP VSTDSDKCGC GRYFASHYYF EEEKDSAAQK
     EGNRWSVAEC TSTFSTDAYG TLRFQGVSRP WKSLYIRMDF TVDPQDMWQL LVHVWGLEPP
     KLVITIYGGG NDFELNPALW QEFKNGLLKV AKNTSAWIIT SGLRVGVVKH VAAALTECTS
     NKKKQQFALI GIAPWGMVKQ SEQLIGQNKC VNYYPFESQR SRFVSLCEGH TCFLMVDNGT
     VGRSGAEMTV RRHFETFLKQ KSMDTSQRLI PIVCLVLGGG RLALHSAVNF VCSSPPVPVV
     VCKNSGRGAD ILAYAVEMAT ESRLKDENLK KLLCDKIKEK LDLEKGEITW WASCLVACLE
     HRNLLTVFDG MSVQNDDQQL DCKILNALLT GRNSTSIDRL SLLLTWNRED MLREILERGG
     DWEESALHSV MMQALMYDHT DFVKLLLQHG VAVDAFLTPD RLEELYNTDK GPPNTLAALM
     QDVAKEGDRC KYFRLPDIGL LIETLVGGGF RANYRRREFR LKYKQYVRGD WTHLPQHPSK
     DAPKPNGNDQ KENSPVKVGS YFFQNPFHDL FIWAVLTNRL EMALSMWQNG DELLAKALIG
     HKLFKAMAKE AKDDALEMEI CDSLRSNAEE FRKLSCELLD QCYRNDDFNT MQLLTYELKN
     WGKKNCISLA ALANNKEFIA HPSCQLLLAD LWLGGMRIRK NVNIKVLLGV LVPPLIFTIP
     FKTKEELLLQ AQTAAEYQEH CDVGEMTSDS ESSDSDSEDD ACCAVVLGEE AENNFEQQTE
     NAPRSPMKRK RKVSHYIPSL HYPDMQSAEQ LQKKHRGTTL QNGYFAKISP TNDPLEFLND
     AASSMPNLSP RGTALYSLKL ANLNRQNLSV SKKIREFYAA PITAFWSWTL GYLFFLALFT
     CIVLVKPTKQ PSWAEYYILM FVVGFFTELI RKLLMVDAKD LRSKWTVYSR RQWDRASLFA
     SLIFFIGFGL RVHSNTLDLG RVILKCIIVF YYLRMLTVLM VSSKLGPYIT IYGKMVSKMV
     LLCTILFVLL ISFGVFRQSL TFPNEEWDWK LIRDIVYKPY FMLYGEVYAD EIDTCGDENE
     NCVFFYWLSP LFMTVYLLLS IIVFLNMMIA AFNFVFVTIS AHSHLIWRFQ KFEQVMDYEK
     QPFLPPPFVI IVHLYLLAQF LCRRRSKAHR TDMSLKLFLN ESDVAKVHDF ENQCMEELFE
     RRRQEMNSTP KAALHDLTDK ISSTNEHIRK LQERLDQYNG RLALIEQLIA KVMPEFVFQV
     QPPSTSSNAS TSPNAERLTV STEDVSSARA CAKSSGHSQT PGPRLRRHNA RWQTEMAFAI
     SPSSSQRGSP ERQFPPRRGN SLIINVRSAN DAGSDDQTHR STTARV
//