ID A0A0V1L0H4_9BILA Unreviewed; 665 AA.
AC A0A0V1L0H4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Vacuolar protein sorting-associated protein 33A {ECO:0000256|ARBA:ARBA00039493};
GN Name=PIGS {ECO:0000313|EMBL:KRZ53071.1};
GN ORFNames=T02_11240 {ECO:0000313|EMBL:KRZ53071.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ53071.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ53071.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ53071.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC {ECO:0000256|ARBA:ARBA00009884}.
CC -!- SIMILARITY: Belongs to the UPF0239 family.
CC {ECO:0000256|ARBA:ARBA00006839}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ53071.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDW01000174; KRZ53071.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1L0H4; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.40.850; -; 1.
DR Gene3D; 3.40.50.1910; -; 2.
DR Gene3D; 3.40.50.2060; -; 1.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR InterPro; IPR009621; UPF0239.
DR InterPro; IPR043155; VPS33_dom3b.
DR PANTHER; PTHR11679:SF85; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A; 1.
DR PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR Pfam; PF00995; Sec1; 1.
DR Pfam; PF06783; UPF0239; 1.
DR SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 604..626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 665 AA; 76000 MW; B8BF0A58F9C5CD3F CRC64;
MHAVIFKLFK DRYSLRRQCF FESCYSQLKT LICSCLPKIM MDASADSSSS NVSFSTVKEV
SRKLLFSALD KWSGSKDHQV VQMLLLRLGS VVSDPSSRIV FLMHPKMRYA AVVADIVHST
LKQFDNPRFH LIFVPQRSVI CEYELKRYDI IKKLSSIEQL PIYFYAWDDD LISMENEWFP
HATASGDYNM ISMISRGLIH LEEIYGPINN IYCKGNMAKD IYDAWSLQRQ TDSWRTLTAF
DSYIDSIIIF DRSIDYVTPM VTQLTYEGLI DEIFGIKCAS VKIQKMESLE DIEEANKSHD
SVGILSTSSG SQDRIQISLN SKQCLYSELR DLNFHAQRHT ANSVREYKEF VKKLPTLQAS
RSAAALHTSV AELIKEVIAS DEFSNTLSCE RGFNVFFSKV LRLMCLQSLT NAGLKTKLYD
QYRREFLQSY GYQYLLLFVE LEKVGLFTKN STDNRNQASS YPNIRKLFDL IIDNHTNELE
PNDVSYVYSG YAPLIPRLCQ QWAKPGWTEI MDSLSKVPGI TKLAAGDERR IKSKNRRNIV
LVLFVGGVTS AEVSALRFLS SQETSSHFLV ATTSVTTGER LLECLAKVSE NIAIELPSES
WFELLVRVGI YISAAFQLVC FVVLFYSHYR SPASSEYTTP STGNCSATRT PHRKMQCRFF
KKKNK
//
