ID A0A0V1L1G2_9BILA Unreviewed; 717 AA.
AC A0A0V1L1G2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Vacuolar protein sorting-associated protein 33A {ECO:0000256|ARBA:ARBA00039493};
GN Name=PIGS {ECO:0000313|EMBL:KRZ53074.1};
GN ORFNames=T02_11240 {ECO:0000313|EMBL:KRZ53074.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ53074.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ53074.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ53074.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC {ECO:0000256|ARBA:ARBA00009884}.
CC -!- SIMILARITY: Belongs to the UPF0239 family.
CC {ECO:0000256|ARBA:ARBA00006839}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ53074.1}.
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DR EMBL; JYDW01000174; KRZ53074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1L1G2; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.40.850; -; 1.
DR Gene3D; 3.40.50.1910; -; 1.
DR Gene3D; 3.40.50.2060; -; 1.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR043127; Sec-1-like_dom3a.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR InterPro; IPR009621; UPF0239.
DR InterPro; IPR043155; VPS33_dom3b.
DR PANTHER; PTHR11679:SF85; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A; 1.
DR PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR Pfam; PF00995; Sec1; 1.
DR Pfam; PF06783; UPF0239; 1.
DR SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 656..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 717 AA; 81907 MW; 3640A17CFE7DC0F5 CRC64;
MHAVIFKLFK DRYSLRRQCF FESCYSQLKT LICSCLPKIM MDASADSSSS NVSFSTVKEV
SRKLLFSALD KWSGSKTLVW DVDLMNPFNL ITGFKELQDH QVVQMLLLRL GSVVSDPSSR
IVFLMHPKMR YAAVVADIVH STLKQFDNPR FHLIFVPQRS VICEYELKRY DIIKKLSSIE
QLPIYFYAWD DDLISMENEW FPHATASGDY NMISMISRGL IHLEEIYGPI NNIYCKGNMA
KDIYDAWSLQ RQTDSWRTLT AFDSYIDSII IFDRSIDYVT PMVTQLTYEG LIDEIFGIKC
ASVKIQKMES LEDIEEANKS HDSVGILSTS SGSQDRIQIS LNSKQCLYSE LRDLNFHAVG
STLSKSIKEQ RHTANSVREY KEFVKKLPTL QASRSAAALH TSVAELIKEV IASDEFSNTL
SCEREFLNCI DSNSLSTFIE QCINKKEPML KVLRLMCLQS LTNAGLKTKL YDQYRREFLQ
SYGYQYLLLF VELEKVGLFT KNSTDNRNQA SSYPNIRKLF DLIIDNHTNE LEPNDVSYVY
SGYAPLIPRL CQQWAKPGWT EIMDSLSKVP GITKLAAGDE RRIKSKNRRN IVLVLFVGGV
TSAEVSALRF LSSQETSSHF LVATTSVTTG ERLLECLAKV SENIAIELPS ESWFELLVRV
GIYISAAFQL VCFVVLFYSH YRSPASSEYT TPSTGNCSAT RTPHRKMQCR FFKKKNK
//
