ID A0A0V1L3W5_9BILA Unreviewed; 1671 AA.
AC A0A0V1L3W5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 13-SEP-2023, entry version 22.
DE SubName: Full=KN motif and ankyrin repeat domain-containing protein 2 {ECO:0000313|EMBL:KRZ54102.1};
GN Name=KANK2 {ECO:0000313|EMBL:KRZ54102.1};
GN ORFNames=T02_12800 {ECO:0000313|EMBL:KRZ54102.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ54102.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ54102.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ54102.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ54102.1}.
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DR EMBL; JYDW01000146; KRZ54102.1; -; Genomic_DNA.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0030837; P:negative regulation of actin filament polymerization; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047184; KANK1-4.
DR InterPro; IPR021939; KN_motif.
DR PANTHER; PTHR24168:SF21; KANK, ISOFORM D; 1.
DR PANTHER; PTHR24168; KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF12075; KN_motif; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 1489..1511
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1561..1593
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1594..1616
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1104..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1228..1256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1356..1383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1114..1131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1367..1383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1671 AA; 183213 MW; D3F7AA19B6D96337 CRC64;
MNSCTGDFWK PTGSHQRCTS TKKSNTNLPL SNFSGESKMT QCCCCPYGYH IDLDFVKYVE
NINSNRQLPQ CSNSSESGPG EEESLSNKGG RKCSAFSTKL FNRRNSKIIR NIGKPVSEAL
CSLRTDEHSP NYTRHVVSSF DSSSKNDHQP GNASISTCIF SDSLENVMSD FEETLSRSSG
TFPRNKQIEN CSTNFVDTDS RLPLYKTVAS KASSSRTTGC TESDFGYNST SNQSMPDSKQ
NLPPNNNSND TSAIYGSSFE SGSSDLQTHL KKLSAIKGAA DDDGCTFSSN KSFLPHITGQ
LAENLENLAN AFLSSTTGQC LSNDFCSDND DHSAPNSKAL NGISDLLQAI RHQMNLSVNH
IQHLEDQVKL IPQLNFQILT LKKEREELSH ALEAAEQRFL QRNYSCSVES AKNASAFVGL
KKYETSAENC SSFVKMQQNC SEFRGKASAK QDCSFATTAN RAVCEKQITM QPTSLGCSSS
SDIKPALFEH KRKLLDISSF PSVRRSSSDF NTTISSRRTR FGRDEDYASD SELAIGDSFL
NRFASLRRSR QLLGSRMKSP CFEATIFQQK RQHQFANNSS LSRKPTSTQS TDVHSLLNNS
VDVQRNKLHS SLDKMPNVCS LLEQSQSRSD SKSAQFEPKS SGVDDHPLKR SPDANILNGT
SIRRRCISYR PLGLVTAERK MTVDVATNVD IRRHVDQSTS CSPGISFTSN AGTQTGDYVC
QQCTASVKTK VTCASVQTQK IHCEVCEARK SLKYLSLGVS TDNVARSEVA VLTDEKIVES
KATNTENPLR CAAQVNTDNL QLESSAFQVD SKIILNSGFW KHASVNTEIK PRMSIGINTQ
PFQDQVKVLF DATTNTEAVD KESKSVTAEP KTENQEISAV VVSCSSSAVG TETNDLVVKK
DVAVNTGCSS IATKSTASGT EKLTSNSVAT STDLVKIIAN NRTMSVGCNT LQSAVKNVTC
STDSSSTTEC GVLAAVVSDD AAVMAVKNTK AVSTSTDMDQ LARFEGTSAS DVYLCKDDFE
TSSSEISKMK VPEMNYSTLN SMNCLNNPKA TTDNVKSFCD CCNEKSKLCF ENKLDSKRTS
LENCLDKYSD KCCMTKLDEV SFDGKESEKS NDSGSCDELN SAPSSETYTD EDMGFFNDRL
PCFVDNEPEK MNTKRRFDFT KPRPTRAFNL SKAAAAKKLL TSQTENQTRK CQPNTSASRF
QRFALQSKSL RVDSKNKGDH LAFFTDKQAA EGRKSAISNR SSSVAKEEEK EDGLSKKVHT
KKINADKKST KRLPARPVNS KFKNWNAAKL NSDTNAQTTA ATNEEQYIEK VEEVDTVGPL
PSEILSSVAR SKIQGNFQNH ITVRLKIHDL ACSTEKLSER ENPPLSSDND ESSATESDSS
FDEGSYDISG VISHQCDVTE NAMSGQATST SSLPDKLIEA LQLLNDAINC AKNVRNEKLE
VTEHYVEQAW LKAAARKAAD AAYVEMFLFT VKSLSTKLLK HLVNICDQNE NTALHYAVSY
GNFEIVSLLL DSQVCDLNKA NKAGYTAVML AALTPLRSDR DRMVLQRLFH MGNVNVKATQ
HGQTALMLAV SQNKLESVKL LLEAGADVNL QDEDGSTALM CAAEHGHKDV VRLLLDVPEI
DATIVDQDGS TALSVAVDNG HKNIGVLIYA HLNYGRKSNQ DWQMVGNQEG L
//
