ID A0A0V1LHP1_9BILA Unreviewed; 587 AA.
AC A0A0V1LHP1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=E3 ubiquitin-protein ligase MARCH2 {ECO:0000313|EMBL:KRZ58986.1};
DE Flags: Fragment;
GN Name=march2 {ECO:0000313|EMBL:KRZ58986.1};
GN ORFNames=T02_3852 {ECO:0000313|EMBL:KRZ58986.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ58986.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ58986.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ58986.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ58986.1}.
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DR EMBL; JYDW01000049; KRZ58986.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1LHP1; -.
DR STRING; 6335.A0A0V1LHP1; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR011016; Znf_RING-CH.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46065; E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR46065:SF3; FI20425P1; 1.
DR Pfam; PF01391; Collagen; 2.
DR Pfam; PF12906; RINGv; 1.
DR SMART; SM00744; RINGv; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51292; ZF_RING_CH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 378..443
FT /note="RING-CH-type"
FT /evidence="ECO:0000259|PROSITE:PS51292"
FT REGION 151..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ58986.1"
FT NON_TER 587
FT /evidence="ECO:0000313|EMBL:KRZ58986.1"
SQ SEQUENCE 587 AA; 62755 MW; B624662F3510F7D5 CRC64;
LSAVNFKALL TNWIPTEEPT FISILRVVLA TMQLEHPRPH IMDENREKAY RLVAYTSVLF
SVLAVSTIGT TYPAMYTYIY NSQQKFNKES MWCQESNEII LNHIRKLRTF TGALNRTARH
TYGAAVPSWG ESAFNGGAQY GPSRCCRRGF PGRPGIPGRN GENGRPGMPG APGMPGISQK
SCEAKVELPC PQCPAGPPGA PGSVGLPGDV GRIGDPGRDG VDGMPGRAGI DGKEGMPGVP
GLDGQPGEPG RPAPYLPISH GECGEPGMPG PTGPAGPPGV SGNDGIQGPM GPKGVKGSLG
PPGLPGNIGF TGPQGMMGPP GQPGLCATYC ANDGGVFHDP SAPAPYGPFG YRTDVNLYET
TACDGKNVQR SPSDELHSVN NGPAVCRICH GSELSSPTKG EPLLSLCKCR GTMGLFHPSC
LETWLSISNT DKCEICHYQF ATERHPKCVT QFIKSPGSPL VMRNMITDFM CFLILTPLAI
LSIWLCISGA LYYGNYSATA VEVSGLICLA TFLLLTYSIW LLVTLRYHCQ IYYSWQEKNQ
NVKVHFVRKF APSSPFLPSS EILSSNSVGH DVNNNFIYSA LALQNSV
//
