ID A0A0V1LLL1_9BILA Unreviewed; 2026 AA.
AC A0A0V1LLL1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Latent-transforming growth factor beta-binding protein 2 {ECO:0000313|EMBL:KRZ59950.1};
GN ORFNames=T02_11231 {ECO:0000313|EMBL:KRZ59950.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ59950.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ59950.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ59950.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ59950.1}.
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DR EMBL; JYDW01000035; KRZ59950.1; -; Genomic_DNA.
DR STRING; 6335.A0A0V1LLL1; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 4.
DR Gene3D; 2.10.25.10; Laminin; 15.
DR InterPro; IPR006150; Cys_repeat_1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR24039; FIBRILLIN-RELATED; 1.
DR PANTHER; PTHR24039:SF28; FIBULIN-1; 1.
DR Pfam; PF12947; EGF_3; 2.
DR Pfam; PF07645; EGF_CA; 6.
DR SMART; SM00181; EGF; 21.
DR SMART; SM00179; EGF_CA; 14.
DR SMART; SM00289; WR1; 2.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 7.
DR PROSITE; PS50026; EGF_3; 8.
DR PROSITE; PS01187; EGF_CA; 5.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1995..2016
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 440..474
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 477..515
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 516..556
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 654..692
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 999..1041
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1042..1082
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1607..1646
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1647..1688
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1702..1938
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
FT REGION 1578..1601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1581..1601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 443..453
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 464..473
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1010..1027
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 2026 AA; 224124 MW; 9BACBCFAB77E505D CRC64;
MTSRNEIYFQ NKFKNLQNDL KPLNNYLHLS ACDSTKSANT PRWKYSLNKY ATKETLVNKK
PLSPVTNIAL VDRKKEQYPR MPVTNFEDEY YSNQISDDYV KLIRYGYKSD AQVQLNANLS
DFQGKNVKFP SAENVHVDLL NTPQGSNFYG DNARKKMFST FPSEKKERKL FFSNSRCFKT
QLVNPTPINP LLRAKSVNSI DAEIKFANKD DTKKDLFNIN NRLLFSDSGR NLNNDGRELS
KQYAILQKMY HDWQDVVKGH EEIRVQGKKL NNEAVENFKN FQLAMLHQLN IVQELCNEFL
QNEKSDIKNV TKSCSDQSTF ENSDSSPPNK VDSLSKISSY KMYRLFLNGR YPSSSDGFYL
LYLSFLEIIE CDRWQSSSGA KEVLHHKSTS IINFDLSLVV CQSSENDQQL AIFPISGLCN
GRAQCFNDAV IKEDQFTFCS NECLPKCGPH GACLKVGQKA RCFCDNGYSG KYCTIQEPNE
CASRPCHFLA QCTNATGIFG CSCLDGFEGD GYNCTDINEC ELPSKQPLCP ENSVCHNIPG
SYFCDCATGY KSKNGLGGMC EDIDECEDKT HNCTSLEQCI NTDGSFRCES RPCEIGFEKI
NGVCHDINEC KTSNACSPDQ SCINLIGSYK CIDQISAGQS KSTSKIDEID ACLVNESCVK
NASICHDRAV CLSQVDKCAC TTGYEGNGIH CIDINECAKD KYICPSETNC INLDGGFTCC
DSEKSKEECL KTKHIICKSD NECRSNSKCI DHHCKCQQGF HLNENLECID IDECSSFSTI
CPEKNWCVNL PGSYVCCNDT ASVSQCLGII IYAPVQKGST LNKKISAGSS SQQITVVPLP
DVKTTPIPQY HTDMVYITPD TEISSSSLNF EEFNSGDKVT NELTDQNFGS GLGSGSGEIS
VDLLSSASPN TAEITSELIS ELNTASTERP DLDYEQTEGA TESIQSTDST SILENKKNIE
DENDKSLTTA QVDSSIRMES EETIDEIESE YVRPAVDYFE KKCLLNESYC HYHAKCLKAN
FSDEFVCACD AGFQGDGYHC EDVDECIYSD KICSPLATCV NTIGSYKCIC KPGYAGNGTF
CSPLCPRGHK PLTTRCSLEE NGQTCTAGYT CIHGFCCPSQ SAQEEDCSLD PTICHESASC
INKVCQCNTG FEGNGYICKD INECALHLDN CVPPLRCQNT IGISRYCSIL RPSCGPNAYC
RNNRCACKDG FILDNNACVP DPNNCSSNRM LCDPNATCIN GKCTCSAGYI GDGLKCYPDP
QDCHNNVSLC HQFARCIDRR CECIPEFSGD GITCFPNPVP FYKNCTINPS VCPTEAQCYY
GRCVCKVGST NLCNKTNLVI INEKNDCRMD PSICHTNAVC RKGICICKKG FIGNGFSCMD
DPNDCLKNKG ICSPNAICVL RRCKCKAGYV GNGISCVPSN QATTCSSNKD LCDVNAECIS
DKCVCREGYL GDGMHCSADK EDCIINPSLC SANAQCISRR CVCQSGFIGN GKTCNESKSD
PSSQKNKCEN CDFNAVCEDN KCQCKQGFEG NGTLCYNNAN IRCDDDAKVC GIHATCISFG
TKMVCICNKG YTGNGRDLIK STTEPNKEKE NGSKETSTLQ EKKEEKSDNL CDSVKCGPNA
ECKINMSGLP ECRCSRGFTG DGKECYDLNE CMLRISKCHH LATCVNTIGS YVCQCPDGYA
GDGVRVCSRE IKVSNLNYID TICEKNGITL QMTNRSDLYG KVYVKSQSEN PDCSQTLPKK
LNNSFKFTAR FEKCDFKKEA EDTYSVIMVI QKHPSFITTG DEAYKLVCTY PSAEREVHES
LSVETLNSSA SYVEKSVGSK CILDVVDANT GKAITEATVG QKLQMKLRAE SSGNYELYGT
NCVVINMETG ESFALTDEDG CAVEEEIFPN WKKMGNSLYS EFITFKWPET ATVRFQCDCS
VCAHQCPERK CNSKLKSPKK RSTTSTSNAI NNQNYVQSNI LKIISDGNLE SEVKLDEIID
WDNYDNDKIC VDGTIMSALF GFGVIFLVAA LCALFFKQLA NIRNDI
//
