ID A0A0V1LTK2_9BILA Unreviewed; 1788 AA.
AC A0A0V1LTK2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Protein polybromo-1 {ECO:0000313|EMBL:KRZ62837.1};
GN Name=PBRM1 {ECO:0000313|EMBL:KRZ62837.1};
GN ORFNames=T02_15058 {ECO:0000313|EMBL:KRZ62837.1};
OS Trichinella nativa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6335 {ECO:0000313|EMBL:KRZ62837.1, ECO:0000313|Proteomes:UP000054721};
RN [1] {ECO:0000313|EMBL:KRZ62837.1, ECO:0000313|Proteomes:UP000054721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS10 {ECO:0000313|EMBL:KRZ62837.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ62837.1}.
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DR EMBL; JYDW01000005; KRZ62837.1; -; Genomic_DNA.
DR STRING; 6335.A0A0V1LTK2; -.
DR Proteomes; UP000054721; Unassembled WGS sequence.
DR GO; GO:0016586; C:RSC-type complex; IEA:InterPro.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR CDD; cd21984; HMG-box_PB1; 1.
DR Gene3D; 2.30.30.490; -; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 6.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR037382; Rsc/polybromo.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16062:SF19; PROTEIN POLYBROMO-1; 1.
DR PANTHER; PTHR16062; SWI/SNF-RELATED; 1.
DR Pfam; PF01426; BAH; 2.
DR Pfam; PF00439; Bromodomain; 6.
DR Pfam; PF00505; HMG_box; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00439; BAH; 2.
DR SMART; SM00297; BROMO; 6.
DR SMART; SM00398; HMG; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF47370; Bromodomain; 6.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS51038; BAH; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 5.
DR PROSITE; PS50118; HMG_BOX_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000054721};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 53..123
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 210..280
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 362..432
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 525..595
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 714..784
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 981..1101
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 1188..1304
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 1381..1449
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 1462..1490
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DNA_BIND 1381..1449
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 141..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1420..1447
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 147..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1788 AA; 205105 MW; DA99750FDEB37B0D CRC64;
MSMKRDHSVD ESTMADVPMA KRLRRSALSS AAEEQARLCR ELFTSLREFT NSEGAYISRP
FLRLPSKKSL PEYYSVIENP IDLTQIHEKV KTDEYSHVDR FMEDINLLVE NAKRFYGEGS
SEYADASELW NQIVELRSKQ EYNSDSHSEI STRSPESSPS RSSRSYRSFS PHRLHRTKEN
PSPMSGCEPV SAHVFEHLLA SVLRERSEGG GRLLCDAFRL LPSKELWPDY YETIRDPIDL
QLIAKRVRSG RYRNLNDIER DFNLLCRNAR LFNEPGSQVY RDAKTIRKFI LKKKAELLDV
GCKSIDRNLM SNDSAVVDCL LNLTEKDLAM EEDSDDEQLP LETERQVKYL YSFLRNWREN
GADESIVEPF LRLPDKRTNA EYYNNVESPV SFFVINKRLK NGCYENVNAL LEDIVQLCSN
AKATNLQNSF LYNVSELRAV KLEELACRKV REMNNMPGTS EPCTSTSTGR ADYLEVDDSE
SGFSSVNSPA VQMDTTSPEL DESQAVFKEK LLTVFNAVVN YRDETGRFVA SAFMEKPSKK
LYPDYYKVIP EPIDLNTIRN AIEADKYSSS QALAADFELL FENARHYNED YSVIYTDANT
LNRIFLATMS RVCPTPIYST KANHFINRGR KSFSRESTLG SCLRLRSGSD AANTITTTAI
TAPSVATNIA APTTSPVQRF QRAAAARGVG MCNNNLEVKL QTLFRRVRDY ADCRGRVLST
MFQKLPPKSD YPDYYEVIKK PIDLQKIQSR IMLGQYERLD ALVADLALVF DNACKYNDPE
SQIYKDALML QRVMLLKQAE LQSDEKTRGS VNVQVAVQEL LMNLFLGMQT YIGSQGRCVF
DSFYRMQEIF DVDKESLTFE RIKRNLEKKR YRRMDRFQQD IFHLFSEIRR YKGPGDQMWN
DAIELQTFFI RTRDQLAKRG EWFYSPAMAF SEKDLHREVE EDCKAFKLRS EIEEKRDHLK
TLLSKHKLGD IDMTKHEWNG VCYCIGDFAY VKPIDSNSTR MHIMQIHRLW KDSGTNEMMV
FGRWLYQPWE TYHLLSRTFL QNEVFLSEKF DHIDAKRLSG KCCVLFIKKY LQYRVLNFDE
KDVYVCESLY IKRGKQFRKL LTWDTDLPGA EWLQLEERSE PLVPVRVPSI FAQTNEQQQS
SAGNVSFEDF DHDCSVLQME RVEVIAPNDN SNQTGEVDFE QLYAQEGIWL KLGDSVYVRN
SDGDSKIVFV ERLWKAGNNQ AFLSGVTFVD PSRVEHEPTR LFYRNELFAL DNSQSFPVSS
VYGLCAVLSY KDYCAFRPTE LTEEQIYLCD LRVVLGQQSK LIIPESHEKK FRFKAFRLSA
DVLEDEILFF KKTVLPEKVA SPYLMKRELA MNMDDYVADS PDQDSSDQFM FHDIQSTPKL
TSRSKSGYIL FSAVARKRIM AENPDCSFGS ISKIVGAEWK KLSKSEKKRY EEEAQRIAEE
REKADADVGG RFHLLPGQIR VYCCRWKDCD YQFENAEQLN EHVTNVHTAQ IVETGDNQYV
CLWHTCTKYR KDGRPFPSMP RLHRHIREKH VPASAKCIYA QNRSRNYMPL AVVDSPRACD
NFSPSTQPTV APQVAQSILA AQLLSQPVAQ TTQGGVYPYP TTSLQSVHYS HNVEASTHAI
HPENSRLIYE NQNMPMYAAL PQNSAARIPA EVANLHSNIE ANVVAETNQP SYGIQEGSVV
VQPGQQQMMD RFGAPVQQAP SSSAAAEESL LPVFIAIPKK PNPISSDAAV YLSAIEGILS
GASSRSGNVV HVGKYFSKIP QTDEELIQGY LRMQRRLFLE GQETRGMQ
//
