ID A0A0V1N4D3_9BILA Unreviewed; 1216 AA.
AC A0A0V1N4D3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Breast cancer type 2 susceptibility-like protein {ECO:0000313|EMBL:KRZ78590.1};
DE Flags: Fragment;
GN Name=BRCA2 {ECO:0000313|EMBL:KRZ78590.1};
GN ORFNames=T10_6289 {ECO:0000313|EMBL:KRZ78590.1};
OS Trichinella papuae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268474 {ECO:0000313|EMBL:KRZ78590.1, ECO:0000313|Proteomes:UP000054843};
RN [1] {ECO:0000313|EMBL:KRZ78590.1, ECO:0000313|Proteomes:UP000054843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1980 {ECO:0000313|EMBL:KRZ78590.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ78590.1}.
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DR EMBL; JYDO01000011; KRZ78590.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1N4D3; -.
DR STRING; 268474.A0A0V1N4D3; -.
DR Proteomes; UP000054843; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 4.
DR InterPro; IPR015525; BRCA2.
DR InterPro; IPR015252; BRCA2_hlx.
DR InterPro; IPR036315; BRCA2_hlx_sf.
DR InterPro; IPR015187; BRCA2_OB_1.
DR InterPro; IPR015188; BRCA2_OB_3.
DR InterPro; IPR002093; BRCA2_repeat.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR015205; Tower_dom.
DR PANTHER; PTHR11289:SF0; BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN; 1.
DR PANTHER; PTHR11289; BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; 1.
DR Pfam; PF09169; BRCA-2_helical; 1.
DR Pfam; PF09103; BRCA-2_OB1; 1.
DR Pfam; PF09104; BRCA-2_OB3; 1.
DR Pfam; PF00634; BRCA2; 1.
DR Pfam; PF21318; BRCA2DBD_OB2; 1.
DR SMART; SM01341; Tower; 1.
DR SUPFAM; SSF81872; BRCA2 helical domain; 1.
DR SUPFAM; SSF81878; BRCA2 tower domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR PROSITE; PS50138; BRCA2_REPEAT; 3.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000054843};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 823..864
FT /note="Tower"
FT /evidence="ECO:0000259|SMART:SM01341"
FT REGION 477..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ78590.1"
SQ SEQUENCE 1216 AA; 135401 MW; D0F6D809402C2FCE CRC64;
LQLENMETDE KVQNSPERII QNAKIGDVLD DSFDESDPFI SEMIKAASTV ATSSGNTECG
ATGKAVLNSS FLGASQIKRK WPSCRSMELN SESSQNKRIR NISPVEELFS DSKNSGDVSF
SRCITMDNYQ NVANVDNEES SLHCKTLSGF KSASGKDCFV SLKALEKAEH FFEAQDITMV
GEVPSGSNET SDFPSTEKDC TMPAVVNLSV VTSAETENEI CGFSTAAGKR CTVNSASIAK
AKELFNSALG EISSGPSVSS TALKDPVEND DDQLNSVKCI SSTSENVQEN SETEHSLPGF
VGFSTASGKK CSYSSEALEK ARKLLNSVDT DESIPFSKNV SQSCVESTSS TDRMLLSSSP
SVDTNSGKMM KISGMAVPRG EQSFAKSVAG DKKYIPIRSA SLMSKFKPNW NNEKKIKLFD
VCQTPSPSGL SSRWRAGRSS TVMRGTPCTR PYVQIVPRGK LNRRFLYRTV QSESENLEAK
HTDVADESDS ASLKSSSTKL NQNTMQPART VNAGGGKLFK LWKSKSKISN YSKFCLKTKP
QSCLSEGELL AMGVREPTLR VTRKTSSEFY FTADYVNSEP NSEIIVADNV IVKVDHQGGI
SMDEIIRGFC RSSDVDSKLL NNDWIRNHLQ WIVFKLASLE MQFPSCLAAR CLNVDNVLLQ
LRYRYDRELE HAQRPLLRKV LNRDYPATAP MILRVVEFEN MDEEFAFFQC ITVELTDGWY
GINAKLDACL SDLAKRGRIQ VGMKLFIINA TLHGAEGGCE PLEAPCNVRL ALTINGVRRA
RWWARLGYLR VTKTPAFPIS SLREGKIVAV KVILCRKYPP VYLEKYADGR SVMRNERCEE
QISLRFAEEV DHLMETMLER VVNDACEFDV DSKGGGGSFL STTSSMEEIY NEDDAEQLLH
LYNKCPDPER FQNMITSSQL NSILKYKNRL DEKRAEKLRE MLERDMATLK ARQQLRTVVP
ILKLRISDFD ALNHGKSYIL NIWRPDVDEL DARLREGNAY SFYQLQATLS RSASGEIELN
SEKSTRIVEL NIRSGCEQNL IEEKFQHRTV TLLGDLQRSD FQAAYDEVDI VGFVIDIASA
TDVDTVYLGD QEMNIVALKI PGGLQNFGWE KVLIVGNFIA CQNLHYKRLS KARIPQLCAT
IVTLIKESPK ESNLSCSLKS LKAEVLKRPE FLNEARSAFK ALLRGSSTRT SLNTSASSIH
LHSNPSVNQQ FKSPVV
//
