ID A0A0V1NU15_9BILA Unreviewed; 1542 AA.
AC A0A0V1NU15;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=mog-1 {ECO:0000313|EMBL:KRZ87452.1};
GN ORFNames=T08_6435 {ECO:0000313|EMBL:KRZ87452.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ87452.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ87452.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ87452.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC PRP16 sub-subfamily. {ECO:0000256|ARBA:ARBA00038040}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ87452.1}.
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DR EMBL; JYDM01000100; KRZ87452.1; -; Genomic_DNA.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0022414; P:reproductive process; IEA:UniProt.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF91; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000313|EMBL:KRZ87452.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924}.
FT DOMAIN 521..685
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 699..883
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 33..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1282..1321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1143..1177
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 73..102
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1297..1311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1542 AA; 175011 MW; 4C82954AC0162D05 CRC64;
MTFYLYEEEE ICTVAMEEED SKAVIGDDDR SLHRLEGSKQ TGGGLVIKKR KEDNKSLDPK
VSLLGLDKLA EAKRAERRKE VEEREKVRRI MDKRHYRSTD EDLGSGVTDS VRGRISNWVE
KRNHDEGRGL AASSKKATKR GHRRDVKREQ DVDDDDDNCG WSSKRKSRPQ QPATPVFKVP
FTPSRCRWDD EEVYRAQSGG RFRSRDLPWN SPAPGLVRPT SSSEVSQTAR WRRQHPGSCS
YRDDREDEEE GRIIFNSEQE REEWEDEQRR LDRDWYAMEE AQECLDEEHN PFYWVSDEYR
KRREEHFEEQ QQNKMKKNKK PLTARQLQIK KDNEKWENNR LFRSGIIDKL ELEEDELLLE
EDAESRVNLL VQNLVPPFLD GRIVFTKQPE PVVPVRDPTS DMAIIARKGS AAIRAWREKE
ERRRDQEKHW QLGGTQLGNL LGITKQQQSD SNSQQVGGGT EEDFADDYKA RNRFAEHMDN
DGAGSAGDGT AGGGASEFTQ KKSLKEQREF LPVFAVRQRL LNVIRENSVV VVVGETGSGK
TTQLSQYLFE DGYADRGLMI GCTQPRRVAA MSVARRVADE MGVALGEQVG YAIRFEDATS
PATVLKYMTD GILLRECLRE PDLDHYSVVI MDEAHERSLN TDVLFGLLKE VLARRRDLKL
IVTSATMDAA KFADFFGNVP VFNIPGRTFP VQVSHSKLVV DDHVQAAVKQ AVSVHLGAPL
PGDILIFMPG QEEVEATCAL IAQRLDQLDD APPLSVLPIY SQLPADLQAR IFHRAVDNSR
KCVVATNIAE TSLTLDGILF VIDPGYCKLK VFNPRIGMDA LQVFPISQAS ANQRSGRAGR
TGPGQCYRLY TERQYEEELL PNTVPEIQRT NLSNVVLLLK SLGVDDLLKF HFMDAPPQDN
LLNSMYQLWT LGALDNTGQL TKLGRRMIEL PLDPTLSKML IVACEMGCSE EVLTVVSMLS
VPSVFYRPKG REEDGDAKRE KFQVPESDHL TLLNVYQQWR VHRYGASWCA DHFVHVKAMR
KVREIRAQLK DIMDQQKMPI QSCGTDWDIV RKCICSAYFH NAARLKGIGE YVNLRTGIPC
FLHPTSALFG MGYTPDYVVY HELVMTAKEY MQCVTAVDGY WLAELGPMFY TVKESGSSRK
ENRIRALKDM ETMEREMRDA QQQIDEQKAK QEAALRAQWK TPKIATPGRV DPTKSTPHRT
GLKKQRFLGR SASAHVTSRM TSAHRCFGHC DEVFVEVRLC RVGSVVIVLR RATHPISQRM
DVQTDAGHVD VDYIMLLGDQ SSEQLDNSGG SDARTAGEVE SAQQGTVIAQ SKQGRIADKA
RTPDGQFAQS VVLDHQKQKS IVEHMHGMTV DQTQNLEPFQ FTNAEQSQLA VDGHGQIVHV
QRIQMGASVE EHSKNHRIQS VFGFREDVVV DENRPQILTR DSEHHVQQLP ASETVRPAGA
QAHRQAHRTE VHGRAEAELC VAFVAHEHQF QASQRTQLPT QQIEPTTTDQ TARESVENFQ
LVENIQQNFT RKLETVPPAE SPNTIITVTR KQITEHRPTW NM
//
