ID A0A0V1P4C8_9BILA Unreviewed; 850 AA.
AC A0A0V1P4C8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 03-MAY-2023, entry version 21.
DE SubName: Full=Leucine-rich repeat and calponin homology domain-containing protein 3 {ECO:0000313|EMBL:KRZ90955.1};
GN Name=LRCH3 {ECO:0000313|EMBL:KRZ90955.1};
GN ORFNames=T08_8571 {ECO:0000313|EMBL:KRZ90955.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ90955.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ90955.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ90955.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ90955.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDM01000049; KRZ90955.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1P4C8; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF21; CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 829..849
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 699..818
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 436..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..469
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 850 AA; 93632 MW; 877E39EC6743DDBA CRC64;
MAALGPCGGG SSTGTMSRCL DKVFEDAQLA GVLSLSGRNL KTFPCSAGRY DLSDTVYADL
SKNRLAEFPV ELAECGFLET LHLQQNCIRS VPNCVRYLGL LTYLDLGVNQ IQTFPVELCL
LPLEVLLLNN NRIESLPVEI EKLSTSLAEL DLSCNQIAVL PNEIGALKKL RVLNLRQNLL
TWLPYEFCNL ELKIFDVSYN KLSHLDVDLR FMRSVVHLSL DGNPLVFPMA MFCDRGRDHI
FRMLELEAVK RGKAKQAGAD VDTRQISLLP TYRSSVHLIL IFGSAYVEWY FLFFHFSNPN
DYKYLSRDKS GRRQSRNRTI ATDSGYSTLS EEHAKMLVEC LPFGAKVGAG ESTIPLAARK
RSPPVGQESA PLCVGAGKRD SGCRPNFVPP PPPLAASAPF TSCTLLQSVK KSERGGLVEE
VMSACLERMN LGSSSVVDEA ASPDLVVNGR STPEKKRPPP PPPPPPRRNA VSSVQQQQQQ
QQCFKKMPAM EEACRSSPVG EEVMSRATPP KHVKSEIIQA LYTTATGGGG AGGPLKAGVA
KKTEFIQSVY NDGSPQLGQS QSKSTILATI EQQQQHCLSP PLIATVAAVD NSNQLTSPQQ
KKQQTTSSIS CNGRLEATEI STAANHNNTN SNVVRRLSYT KNQQPNRTTI NRNFIFLSFK
NIKHNFALFF FVKFSDPAVR STHNRNNNNT VASLVESPVT VVESIRKIVE QKLDVVDLPH
SAEALGNVLS DGVLLCNFIN AIRPRTVAIV HTSADNGAKL PLAKARRNVE NFLTGCRRLG
VQEDWMPRYE DLVLRHPPDL KTLHELLGTL VQLCRLNRTE HALSFGRHLF LLGCCAIILA
TALRAFNIFL
//
