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Database: UniProt
Entry: A0A0V1PFQ1_9BILA
LinkDB: A0A0V1PFQ1_9BILA
Original site: A0A0V1PFQ1_9BILA 
ID   A0A0V1PFQ1_9BILA        Unreviewed;      5147 AA.
AC   A0A0V1PFQ1;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   10-MAY-2017, entry version 11.
DE   SubName: Full=Ryanodine receptor 44F {ECO:0000313|EMBL:KRZ94972.1};
GN   Name=Rya-r44F {ECO:0000313|EMBL:KRZ94972.1};
GN   ORFNames=T08_10827 {ECO:0000313|EMBL:KRZ94972.1};
OS   Trichinella sp. T8.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichocephalida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ94972.1, ECO:0000313|Proteomes:UP000054924};
RN   [1] {ECO:0000313|EMBL:KRZ94972.1, ECO:0000313|Proteomes:UP000054924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS272 {ECO:0000313|EMBL:KRZ94972.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRZ94972.1}.
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DR   EMBL; JYDM01000015; KRZ94972.1; -; Genomic_DNA.
DR   Proteomes; UP000054924; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054924};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KRZ94972.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054924};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4496   4521       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4696   4715       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4756   4782       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4900   4922       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4945   4967       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   5026   5045       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      103    157       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      164    208       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      218    272       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      278    339       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      344    402       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      582    817       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1045   1226       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4247   4282       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4285   4317       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4260   4271       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    4295   4306       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   5147 AA;  586743 MW;  3AF85289E50EF3A8 CRC64;
     MTDFQENSTG EQDDISFLRT GDVVCLTCLA PCKESGTGSA ERVSLAAEGF GNRICYLENV
     SDKNKPPDNA TSMFYIDQAL SVRALQEMMS SESPNISGSS STHRTLLYGH AVQLKHALSG
     MYLTCLSTSS ASDKLAFDVG LCETNVGEFC WWTIHPASKQ RSEGEKVRFG DDVILVSVAT
     ERYLHMSSTN GNTVLAAFHQ TLWSITPNSS GGVRERHMGY VCGNDVLRLN HGNDECLTIP
     ENWSDSHQNN IVIYENGKSC NQARSLWRPE LIHGKWQSSL IGWEQAFRIR HITSGRFLAL
     NEDNQVCLLH KDRASFESTA FIMISSKDVK RSTFEEKEEE GMGVATVKYG ETVIFLQHLQ
     SNLWLSCQTT AVTKKNMGKV EEKKAIAVEE ARMDDCFILF KAQEEESQSA RVIRKCSQIL
     NRFLRGLEGL QMEGKDSLAW NRADLSETVK LMEDLIQYFA QPEESVDFES MQNGLRALRN
     RQDLFQEEGL LNMIIDTIDQ FSAVESMTEL LDVTKEDKCK NWQDISTYLY LLVAAMIKGN
     HSNCTQFASA QRLNWLFSRL SNPQSAEGIL DVLYCILTES PEALNMINED HVKAVISLLE
     KVGHDPKVLN VLSALCEGNG VAVRNSQNVI CSELLCNKKF LLQTKMIDQV SSVMANIFVG
     SYENSAMYPR WYFEAELEYM ESMRTSGQKP HLRIGWASSA GYRAYPGSGK KWGCNGVGDD
     MFSFGFDGQY IYAGIAALKL SKLIGGIEKF VGTHEIRKGD VIGCSIDLAI PEIQFSLNGH
     QIGTSVRNFS SCDCLFYPVM SLSAIVSCRF FFGGSQGKLR FGPKKGYLPI SEAAITPVKL
     ISCISFGDTR KGYFAGPSTV ISDYIVFQPK PIDTKDVSLP KHLEDVHEKL AENIHEVWAM
     DKIEKGWIYG ERRSETQKTH PCLTSYERLP TAERSYNLNL AKETLKTIVA LGYRIDIGKA
     SNRVKTFRLG QNFLMSNGYK PAPLDTREYE LNETLETLVD LLAKNMHNIW AQSKIQRGWT
     YSKNENVNIK TTSHLVAYDF LDPNIKAANR DKAGQIIRSL LVYNYCIEPP TAEQDEGAVK
     QSQVMNLQKR TYRFEKRYAV KSGKWYFEFE VRTSGFMNVG WMDVSASPDG DFGLHKSSYA
     YDGYLGRKWH GESESYGKKW NVGDVVGCFL DLTDRTICFS LNGELLLDSS GTEVAFDNVS
     AEDGFVPAFS LAPGQIGRLN CGQNVNTLKY YTTCGLQEGY EPFCIRMSRQ APMWIAKCEA
     EFDEINEEEK RFKVTRIPQS GDNPPCLKLQ CKSAGMLERC SLALFRLNLP VFCKEANDNR
     VCNQYFTETL SVRNAGKRNG ESDRTAESSR RGKMKGIRGS RNQDENISFH DQQNYADQYE
     VSNHAVMKSN YLVQKTFSLD DDSSEVTENR FRKAPRLRSS ASEANLKEKE SIDSQDKISA
     SYAVSNTKRN LRPFKVLQSF GQRMRDVSVG RSRKQNARKL QEACASKSKI RSDENDKFSS
     GHLNSRKLDD RVADVDSTES LDMPKSGPGR RPTVIRLESD SKVKKRSNYF SSGHDLLVEA
     SKLSAPSGNQ HVSIGASVSF YSTPDDYYFG VRVFPGQDLA NIWIGWLTPQ FSFTGSQIAA
     DSQRICFLES THSTLDNIQE FRSCYIVNGM ELLTAAGGSS SVSKMAGILA GCLINTATGE
     LKFHVNGKQT EMSYRVEPGT ILYPAVFVLP TSREVLQFEL GNIEKTLPIA SAQLNERSNA
     VQLMCPPRLK MEICKTRTWL RVPDQCARVT SLKLSDTRGW SVLCDDLVRT MMLYVPERDS
     SIDILELAEH ESLCTFHQQT LRLYCSLCAQ GNFKIAHILC QHVDEDQLMY AIQSKYLSGS
     LRQCFYDVLI AIHLKCHYDA RLAESHEYII PLNAKLKDRN YFNYETKSVY PHALNSDITL
     KSSINVMEVK KKISTEDEKF LMSPTFDFHT LKQYVVDALE EATLEALMNS RDLIGGTNTT
     HFLPILKLFD TLLLVGVLSD TDIHRFFRLL NPKSFQETLD SPQNVKGLVD LDLDEMVQLE
     LCHIMNHLCD LQLQGRVESL INFAETFVGE TQNACALDEI FEKSNLCFNY LRVIYLEIKQ
     TDMPSAEAAR KTKEFRCPPK EQMLKLLDFK ADRDEQTDEE GELEVSAMSE FLQRVLREFH
     CNMVKFIGNS DKNDDNYSAN VEQKQLESEN MNWVEKLAWM VVPVPPALLS EDERIKFDGE
     EAFRNIILST LIKWTGNKAI DDPNLIREIF GLLLRQYTRI SEVKSALKTA YCIHERSIED
     VQSFLDNLCQ IRRLLCVQFE ATEEEVLKNS LWDMMNNKVF FQHPDLMRLL KVHENVMTIM
     VNVLSRAQKS ELDDRRNRST QDDMKKAFQN SISDLVVACC KFLCFICRSS TKNQAAMFEH
     LPFLLDNATM LLAKPSLRGS VPLDVAYYSF MENSELALAL KEDDLEKVAF YLSRCGLQAN
     AEMVFKGYPD IGWDPVEGER YVDFLRFCVW VNGECVEENA NLVIRLLIRR PECLGPALKG
     QGEGLFRAFK DAISLSSEIS NLHKGRDLRS RFNFDLSHYP NPEIEEEDYI DLGAAILGFY
     SSLADLLGKC APDHLTVKSG KGESVRLRSI LRSLTSVEDL EAILALRFLL PNVFAAKEES
     SRSSSIGLLP CHKQSILLFL ERVYGLIDKE MVFRLLEQSF ILDFRAATIL DHPAYAESDL
     ALALNRYLCG SVLPLLTSHA HCFADAEHYY SLLEATLHTV YRMSKIKSLT KSQRSAITEF
     LLAFTKEIHP GMMKKLLQKV VVDISSLNEF ATVPLQIMTQ HYECFSKHYG ISMHEDTASE
     EQKRLSMLLF TTIFDSLGKR AFDSDLFASA LPCLTAIGSA LSPDYAMQSY AEEEIQNMNV
     PSGHMEVWRP HPVDASNVQL SVNLQNLVQR FAQHFHDSWA SRKLEKGWRN DDIYSRTNCT
     HPRLKPFGML KEFEQNFYKE RCSECLKALL AWGYSIEQET QVSSVQPKSM NPTSNVRSAS
     VFCPQPIDLS NMTLSEEMCE LAERIAENSH LIWVSKTIED LNDANTGIMV LLVPWDILAD
     SEKRKHRFRA QEVLKFLQYQ GFRLKSPLHR AREEYQQTVV DSNTHRPVEK RFACNLLEKL
     LAYLENAAQK MEVIKPSKQF SRYRNYTLPS EDVKFFGKVT DHIILAINLI FCLLKVLLPL
     LESYFRSHRN YFTAASSASL SGVASIKEKE MVAGLFHRLM SVFRSKHNAF GCHVKSTVRC
     LQVLLQAIDF RSLVKINSDT LRTCAQIFLS NMVSDLMNIT KEIKNNGRYA EIKGKTLPCT
     SSLLFLYEAM LPLLTTLFCH LSKHGHGQDF LVNDIQVGCY KIADCLYMLA SPITISRKSV
     KEEMEKHRSS IGQCLSAFAC CFPVAFLEGD FNPNSRGSTV DRQHLLSESK DTSSSLLLNI
     PSLDNLLSNI EQLSNTNGKY QDAPAIFDVD IPMLCSYMSF WWQHGPTNNT QELIKFFFMC
     IMMLYEIYFR KNLSAVSSDH INRLFSACSR LICDHIGIAH ADWICHLAPF ITPMINYVTI
     EPVRDYLLPM AEKVRMQADL AFKEEEKHRM HPDVFDESTV IELHSILIRD VYALYPILIK
     FTDLHRARWL KNPCWETNAL FEHVAFVFKL WSTSQHMKRE ELNFITQFES DFMTGTSRKT
     GKAAVAFRKK KRREGKRREK DSGSIVVACL KRLLPVGLSV FGGRELDLLQ KVKEKYMKKE
     NDEKIKEYIS SSLAVPDQED VFDKSHWQRK LYQQIGKAQM LGIDSMSQEM VLDKIIFMGV
     TLCNLHNVEH PQTFQADAWR KIVSSQRKRA VVACFRMVAL YSIPKHRCVN LFLSAYIEKW
     LKSEKVDEDL LISEVTVASE GRMQRLREDV EEVDEQCPPD PLSQLVQCFQ RAATSERKQL
     VPIVDDNLYI QYVRVMASSI HINDDEQNNA EDDAISMEAQ ELEKQQLLHE QSRLADRGVA
     VMVLMYLSAC NGEPNVMVEK TLALGIHILN GGNSDVQNIM LNYLQEKKDV RFFSSISGLM
     NRCSVLNLEI FERQLKAEGL GMGAELSVGK HQNLNDSEFI CSLFRFIQLT CEGHNSEFQN
     YLRNQPGNTT SINLIICTVD YLLRLQESIM DFYWHFSSKE VVDEAGKAHF LKALSVCSQV
     FNTLTESIQG PCVGNQMALA NSRLWDAING FFFLFAHMMD KLSKNHTQLE LLREFLSLQK
     DMIVLMLSML EGNILNGSIG KQMVDTLAES QQNVQLILKF FDMFLKLKDL TTSQAFQEFD
     TNKDGWISPK EFLRAMEAQK MYSTEEINYL MMCTDVNNDG KIDYMEFTER FHNPAKDIGF
     NLAILLTNLK EHITGDSRLD QILQTASSMC EYFDPYLGRI EIMGSNKRVE KVYFEIKEEW
     LEQFNKPQIK QSKKDFLFNV LQDDGGEQGK LEAFVNFCED TIFEMSHAAE ISSEDRDSRI
     ERAKKQREIF TGMADKTDTI SAFDIILKIM KKMGTSIVSF CRYLRPSELR QLKHSAALHF
     SSMTYGQLIL IFLKIVLFIF VTIFRGAFYL INTFFRFILL MMYGVWEEEK ASSKLTAENA
     VHHTLPKDFN IVPQLYEPEK PEVYEAFGIQ LTQGIGEGLS MKNPNNQPQF EKSFSMHIGN
     SSPFSFASAE SASVQNERQL MIYSNQIPET YTPAAVSVCN DDSNIVVKEI YEPKIAETTS
     SAKGSAFNFL ARNFYLLKYI TLALAFCINA ILLFYRVADN PSNDEKVVLE ADNSKLQNEE
     HMENGIEEEL AIHDNYYYLA HMLIFLSVAH CAASLALLIA YYQLKVPLII FKREKLVARK
     LEFEGMWITE MPSEDAVSGK WDSMIISSPS FPEKYWDKFV KKKVKDKYKD QFDEEELNRL
     LGLDKTVVDS SNSSSSSGVD WCYQIWKLGV IFTDGSFQYL LMYLFFSAVG IWNPFFYAGH
     LIDVVISFPM LQTILKSVTH NGKQLILTVM MVLVVVYLYT VLAFNFFRKF YVQEDDGEET
     DSKCNNMISC FVFNVYAGIR AGGGIGDELQ SPYGDEREAW RILFDMTFHF FIIIILLAIM
     QGLIIDAFGD LRDQQESAQD KLESNCFICD IGKDFFERLP HGFDHHTTKE HNLAYYLFFL
     MHLINKDDTE YTGQETYVWE LYEKRCWDFF PVGECFLKQY EEQLMAS
//
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