ID A0A0V1PGQ0_9BILA Unreviewed; 633 AA.
AC A0A0V1PGQ0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Homeobox protein Nkx-2.2a {ECO:0000313|EMBL:KRZ95324.1};
DE Flags: Fragment;
GN Name=nkx2.2a {ECO:0000313|EMBL:KRZ95324.1};
GN ORFNames=T08_2019 {ECO:0000313|EMBL:KRZ95324.1};
OS Trichinella sp. T8.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92180 {ECO:0000313|EMBL:KRZ95324.1, ECO:0000313|Proteomes:UP000054924};
RN [1] {ECO:0000313|EMBL:KRZ95324.1, ECO:0000313|Proteomes:UP000054924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS272 {ECO:0000313|EMBL:KRZ95324.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ95324.1}.
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DR EMBL; JYDM01000013; KRZ95324.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1PGQ0; -.
DR STRING; 92180.A0A0V1PGQ0; -.
DR Proteomes; UP000054924; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24340; HOMEOBOX PROTEIN NKX; 1.
DR PANTHER; PTHR24340:SF82; HOMEOBOX PROTEIN VND-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000054924}.
FT DOMAIN 340..400
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 342..401
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 43..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRZ95324.1"
SQ SEQUENCE 633 AA; 72524 MW; 48D09010A71F6B03 CRC64;
LFIRREISYL KVAPRLMLTS TGDAQLTQPA ASAETLTSQL ESTEKVDQVV DDNKKQQKQD
QLEDCRPASQ ERLTEQRSKR TTCFSVKDIL QLPSQRRQLS SKNRFAVALM YHHPQPQQQH
HNVSPFHNQH NQQQQQSQQV TLHQHHQQEQ QHPHQLNDLF SATPNTPIND CTHYNHHSVG
HEYTPTSFAK PSHFQYANGV QLHLRHAFDQ APTTGYCNGR MPVATSPSPW LQATFSVRYP
QQTPASAVQT DFYHYRHLSP SSLTDAYMLD QPFHQITADK STRSPIHRQA SAKLDSPNPD
SKQQNSANNI TTDEKHIQNG SELSDKPEPV TAKKQTTSST KKRKRRILFS KSQTVELERR
FRQQRYLSAP ERELLAQQIR LTPTQVKIWF QNHRYKTKKG IHDRTIGPSH LNNSLMSSRR
ISIPLLVHDG KPCTGTRKTL DSVSSLPNPM PLMGAAHFGP LAPDPVTPTP PMGLFAGTSA
THHHHQQQTP APVLGASHYY LQNDKYKMTM WKLSFNSSTF AWSQLSQSAG VLTYRRERFE
YKSDRWNGIV KMFRRPQPKV QLDADDVPTP DQVVRKFGQF RQVEHAMFFT RLEKPTKVVD
KSTSRESVVE WCPDVWWPTA ESLLTTLFAK ALS
//
