ID A0A0V8JJ74_9BACI Unreviewed; 766 AA.
AC A0A0V8JJ74;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=AS180_15000 {ECO:0000313|EMBL:KSU87078.1};
OS Priestia veravalensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia.
OX NCBI_TaxID=1414648 {ECO:0000313|EMBL:KSU87078.1, ECO:0000313|Proteomes:UP000053681};
RN [1] {ECO:0000313|EMBL:KSU87078.1, ECO:0000313|Proteomes:UP000053681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SGD-V-76 {ECO:0000313|EMBL:KSU87078.1,
RC ECO:0000313|Proteomes:UP000053681};
RA Dastager S.G., Mawlankar R.;
RT "Bacillus caseinolyticus sp nov.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KSU87078.1}.
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DR EMBL; LNQP01000054; KSU87078.1; -; Genomic_DNA.
DR RefSeq; WP_062687047.1; NZ_KQ758669.1.
DR AlphaFoldDB; A0A0V8JJ74; -.
DR Proteomes; UP000053681; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 509..719
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 766 AA; 86545 MW; 0BE154F0A8BF21EB CRC64;
MKGFYLYIAV SSMLTMFLAY HLSWITFVFA LSYAVFLYLK CPPYVFVLCV LVGGFSFGLF
YLFSLHHQTS ISSNQTIFTG QIASIPDIDG SQVRFFFSTQ GEDISVTYYM KNESEVKQIQ
NLTIYDQCML KGKLSSFEEG RNPNAFNYKA YMNTQRIHWN LKASTFTTSL CQPPKRLSLI
QSLSTYRQKG IDYLKQTVPQ PASSFMQALI YGERNQIDSD LLQLYQSFGL IHLLAISGLH
VGLMTFMFFY ILIRVGVTRQ LAINILLVTL PLYAIIAGGA PSVIRAVLMS MLALISMQYQ
KKISLTDSIA IAFLLMVVVN PFYILQVGFQ LSFVVTLFIA LSTQIILKRI TSTIAQLLMV
SLVAQLGSLP LLLFYFYEIS LLSLPLNMIY VPFFSTVILP LCLFTFIASF FFSPIGTIGQ
WLLNNILLLS EWFLKLLHDV SPVFLITTGK LSLWVVGLFY IGIYGVLWSM ENKKYTSFFS
IVTVLMFVVQ CLFPYVNPYG KVTMIDVGQG DSLLIELPYR QGIYLIDTGG SVPFFSEDWQ
VRRDLFDVGR DVIMPVLKSK GIRKVDKLLI THGDYDHGGS ASTLLNQVKI EQVVLGKKKQ
FTDLEQDIIK QARKANSEIS YVQKGDHWKQ GDISFYILSP TGSETTSNNS SIVLFTEFGG
LNWLFTGDLE EAGENEILRI IPSLQADVLK IAHHGSKSST SPAFLRALNP KIALISAGKK
NRYGHPHEEV VERLQEADVL IYRTDENGAI TYTFRKNKGT FYPQLP
//
