ID   A0A0V8QGH3_9FIRM        Unreviewed;       709 AA.
AC   A0A0V8QGH3;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900, ECO:0000256|RuleBase:RU361257};
DE            EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900, ECO:0000256|RuleBase:RU361257};
GN   ORFNames=ASU35_01290 {ECO:0000313|EMBL:KSV59655.1};
OS   Acetivibrio ethanolgignens.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Acetivibrio.
OX   NCBI_TaxID=290052 {ECO:0000313|EMBL:KSV59655.1, ECO:0000313|Proteomes:UP000054874};
RN   [1] {ECO:0000313|EMBL:KSV59655.1, ECO:0000313|Proteomes:UP000054874}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACET-33324 {ECO:0000313|EMBL:KSV59655.1,
RC   ECO:0000313|Proteomes:UP000054874};
RA   Zou Y., Xue W., Luo G., Lv M.;
RT   "Butyribacter intestini gen. nov., sp. nov., a butyric acid-producing
RT   bacterium of the family Lachnospiraceae isolated from the human faeces.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC         N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC         COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC         Evidence={ECO:0000256|ARBA:ARBA00001279,
CC         ECO:0000256|RuleBase:RU361257};
CC   -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00006594, ECO:0000256|RuleBase:RU361257}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KSV59655.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LNAM01000112; KSV59655.1; -; Genomic_DNA.
DR   RefSeq; WP_058352185.1; NZ_LNAM01000112.1.
DR   AlphaFoldDB; A0A0V8QGH3; -.
DR   STRING; 290052.ASU35_01290; -.
DR   OrthoDB; 9804186at2; -.
DR   Proteomes; UP000054874; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1020.10; Adenine-specific Methyltransferase, Domain 2; 2.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR023095; Ade_MeTrfase_dom_2.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR012327; MeTrfase_D12.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; TIGR00571; dam; 1.
DR   PANTHER; PTHR30481; DNA ADENINE METHYLASE; 1.
DR   PANTHER; PTHR30481:SF3; DNA ADENINE METHYLASE; 1.
DR   Pfam; PF02086; MethyltransfD12; 2.
DR   PRINTS; PR00505; D12N6MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000256|RuleBase:RU361257};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054874};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|RuleBase:RU361257};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361257}.
SQ   SEQUENCE   709 AA;  83102 MW;  99795DA2097A0947 CRC64;
     MNYTATQIAK KLDISRSYLY YLKENGLIEI ELNEKGRPMW TEEVYDRLKE YIKKNNVEEK
     PEVQKLPYKT TKINNRRYLG NKYKLLPFIT EVIEKKCENV NTVADIFAGT GAVASAFTDR
     KIITNDIMYS NYICHVAWFS SEDYSEDKII DLIIYYNNKV VEQDNYMSEN FADTYFSLVD
     CRKIGFIRQD IEDRFKKGEI NTRERALLIT SLLYAMDKIA NTCGHYDAYR KGAEFEKHLE
     LYVPQPDENL NENNVCYNMD TNELVPNIEA DLVYIDPPYN SRQYCDAYHL LENVARWEKP
     EVFGVARKMD RTALKSDYCT KKATVAFEKL IDSIHAKYIM LSYNNMAEKG NDRSNAKISD
     DDIMRILQKK GEVQVYTEDY KAFSTGKSDI KDNQERLFLC KCYGSEKEII PSALNYTGGK
     YKLLPQILPF FPKDADKVVD LFCGGCNVGI NVNCNKVQFN DSNEYLMGLL DTFKRLSKEE
     IFIWIYETIE KYDLSLVSKN GYEYYGCESS KGLGAYNKDG YNKLRKDFNS KKERDDEYYL
     MLYLLIVYSF NNQLRFNRKG EFNLPVGKRD FNLKMQQKLE GFLDRIKSGD YGFTAGDFRE
     VNIDEFTDKS FFYVDPPYLI TCATYNEQDG WNEQDEYDLL AYLEELDKKG IRFALSNVLE
     SKGKKNEILA DWIKKHKKFK AILLDYDYKN SNYHTKREGV TKEVLVVNY
//