ID A0A0W0FF95_9AGAR Unreviewed; 1456 AA.
AC A0A0W0FF95;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=WG66_12495 {ECO:0000313|EMBL:KTB34954.1};
OS Moniliophthora roreri.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=221103 {ECO:0000313|EMBL:KTB34954.1, ECO:0000313|Proteomes:UP000054988};
RN [1] {ECO:0000313|EMBL:KTB34954.1, ECO:0000313|Proteomes:UP000054988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2952 {ECO:0000313|EMBL:KTB34954.1,
RC ECO:0000313|Proteomes:UP000054988};
RA Aime M.C., Diaz-Valderrama J.R., Kijpornyongpan T., Phillips-Mora W.;
RT "Draft genome sequence of Moniliophthora roreri, the causal agent of frosty
RT pod rot of cacao.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTB34954.1}.
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DR EMBL; LATX01002022; KTB34954.1; -; Genomic_DNA.
DR eggNOG; KOG1027; Eukaryota.
DR Proteomes; UP000054988; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:InterPro.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd10422; RNase_Ire1; 1.
DR Gene3D; 1.20.1440.180; KEN domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045133; IRE1/2-like.
DR InterPro; IPR010513; KEN_dom.
DR InterPro; IPR038357; KEN_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR13954; IRE1-RELATED; 1.
DR PANTHER; PTHR13954:SF6; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF06479; Ribonuc_2-5A; 1.
DR SMART; SM00580; PUG; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS51392; KEN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022527};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054988};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1456
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006901740"
FT DOMAIN 968..1318
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1321..1453
FT /note="KEN"
FT /evidence="ECO:0000259|PROSITE:PS51392"
FT REGION 500..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 869..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1188..1228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..530
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..887
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1195..1228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1456 AA; 158772 MW; 0E945D9385CF1EF3 CRC64;
MAPIFLLSSL FLSFLIACYA DRVSRELAPF SSGAGSSRFA QRQILTEEHA SSSSTGDADP
LGDSDLVDIV LVASVDGKFH ALNRTSGHLL WSMAAKDGFS AGTGNSSTLA PLVRTQHPLL
SNDPNGESNK VTSAYPSPTT EFYIVEPQSG DIYVASTASP LGPLQRFRYS MPELVDMSPF
SFKDEDYQRM FVGRKESRLI LVELETGKIK EVVGTDECRW DPLEFGFGGE EREEDEGTSY
VVDLDELEEG AAEIEYVDDD EYSNSSSTYG DDAKKKKPTE VYIGRTDYHI SIYTKPTSVA
SAKRPVPPVQ NLSFSVYGPN NQDSRLQTTY TRTKDDKYLA SLPSGEVIAF KAHGKGDEKR
ERIPWLWIKP FQNPIVATFD VFRRRGNNDN SPVGAVDNDS ESHTFVLLQP QPSLTDIHPS
LDLSLYQSAP ASEDGGEGSG SQTPLTNILP NADSAYVGIL EETGSLFAMS PETYPLVAFG
GHWAASGTTS RSRLIDGAAN HKYDDDGEED NFISVDELTR RRKEREAETS SSESQSTSSA
SPITTNGAQS TLRANMCNVE DGGVFDARCL VGVRKLADGA GGVDVGKNTD FGGATGTRRA
GVVTFETDAD PEGRWRRLLD PPKRGYGEVY REDYEHPSTS VSRPSQPSQR PTHSSDPTVP
VVEKHVFLGA SSGIIATAFA VALVLVGMWW RGAVGQTALH RLHAPLEPSQ TAKLEPGHEH
SGVIDPNVLA NGITNGDATV DPHIVKPDTI LLQPDTTVIA DAQLAASQST STQDKIPVRH
RANSDVFALS EVQSIPSRSP VQKPSRLPSS PKTSTVKLPQ TSSTPTPPTP KVQSRTRKQS
TSTANRNLID SPRLEESDFE MFEHDGADLE GEGEVDEDGE GENEPEAEGV EAGTPKKSKV
RRGKRGRKKR KGAAAEGNGN GGTPVPAKGK DKENVPVPSP SPAPAATPLT PSMIVVPPTP
AVTQPSLIVS DSILGFGSHG TVVFRGDLQG RQVAVKRLLR SFVTLASREV SILQESDDHP
NVIRYYYQEA HADFLYIALE LCPATLADII EYAAGGGIDW GGSVESRTLG GTGKEGMKPE
EWDDLIRCFD PKKALKQIAS GLRHLHALKL VHRDIKPQNI LVSAGPGRGA RGTTRGSMGG
YRMLISDFGL CKKLDMDQTS FLPTAQGAMG AGTVGWRAPE ILRGEVKLDE SASGDDQSSR
GSSTGTLTNA SIGSTSTTTG STGVSSGAKS TRLTKSVDIF SLGCLFYYTL TNGQHPFGDR
FEREVNILKG AMNLDGLDRV DGGMWSEEGV EARDLIQRIH THHEHRPDTT TCLLHPFFWD
SGRRLNFLQD ASDRFEIMCR EPKEAHLISL EEGAADVVGN DWYSRMDKIF IENLGKFRKY
NGSSVQDLLR ALRNKKHHYQ DLPENVKRHL GAMPEGYLAY FTRRYPKLFM HVHRVIDECD
LKDESMFRTY FELADQ
//
