ID A0A0W0TKB1_9GAMM Unreviewed; 467 AA.
AC A0A0W0TKB1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Guanylate cyclase {ECO:0000313|EMBL:KTC95963.1};
GN ORFNames=Lfee_2325 {ECO:0000313|EMBL:KTC95963.1};
OS Legionella feeleii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=453 {ECO:0000313|EMBL:KTC95963.1, ECO:0000313|Proteomes:UP000054698};
RN [1] {ECO:0000313|EMBL:KTC95963.1, ECO:0000313|Proteomes:UP000054698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-44C {ECO:0000313|EMBL:KTC95963.1,
RC ECO:0000313|Proteomes:UP000054698};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTC95963.1}.
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DR EMBL; LNYB01000082; KTC95963.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0W0TKB1; -.
DR STRING; 453.Lfee_2325; -.
DR PATRIC; fig|453.4.peg.2545; -.
DR OrthoDB; 8724845at2; -.
DR Proteomes; UP000054698; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR11920:SF335; GUANYLATE CYCLASE 32E; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054698};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 293..420
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 467 AA; 53254 MW; 1739E5EE7027E87A CRC64;
MYRFHFKQDY LLVSFFVGLI ILVVALVGCL FLLKHLSFLQ EQSNNRHYES YRIAQELRIS
SDDLTKMVRL YVITGDKKYL DHFNEIIAIR SGTSPRPKEY DSVYWDLVLD DDKRPRPYEK
AKSLVQMMID QGFSLQEFEL LRQAQEKSDA LTAIEFRAIN AVEGKFDTGS DQYSSQGEPN
KKLAIDLVFG KKYMDEKAKI MAPIQLFFEK IKARTTERNK ELSHKINQVI SIAIILSVLS
TVVMLISIIK ALHRIAKTAK ENELLLFNIL PSSIAERLQR GEKIIADEYP QASVLFCDIV
GFTAMMAKIG TNKMFDILGC LFDDFDDLAQ KYGVEKIKTI GDSYMAAAGI PEPAADHAFR
IADFALAIKE KVKTFSQIHA IDLQTRIGMT YGTVIAGVIG HKRFIYDVWG DVVNIASRME
ATNIPGEIQI TEKMALLLED QFVIEKRDEI EVKGKGKMCT YFLKSRR
//
