ID   A0A0W0W1A4_9GAMM        Unreviewed;       768 AA.
AC   A0A0W0W1A4;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=GGDEF/EAL domain-containing sensory box protein {ECO:0000313|EMBL:KTD26279.1};
GN   ORFNames=Lisr_1153 {ECO:0000313|EMBL:KTD26279.1};
OS   Legionella israelensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=454 {ECO:0000313|EMBL:KTD26279.1, ECO:0000313|Proteomes:UP000054761};
RN   [1] {ECO:0000313|EMBL:KTD26279.1, ECO:0000313|Proteomes:UP000054761}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bercovier 4 {ECO:0000313|EMBL:KTD26279.1,
RC   ECO:0000313|Proteomes:UP000054761};
RA   Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA   Pupko T., Shuman H.A., Segal G.;
RT   "Genomic analysis of 38 Legionella species identifies large and diverse
RT   effector repertoires.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTD26279.1}.
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DR   EMBL; LNYH01000053; KTD26279.1; -; Genomic_DNA.
DR   RefSeq; WP_058501513.1; NZ_UGOE01000001.1.
DR   AlphaFoldDB; A0A0W0W1A4; -.
DR   STRING; 454.Lisr_1153; -.
DR   PATRIC; fig|454.4.peg.1241; -.
DR   OrthoDB; 8553030at2; -.
DR   Proteomes; UP000054761; Unassembled WGS sequence.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR012226; Diguanyl_cyclase/Pdiesterase.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF12860; PAS_7; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   PIRSF; PIRSF005925; Dos; 3.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054761}.
FT   DOMAIN          216..283
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          286..338
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          370..503
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          512..766
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   768 AA;  88274 MW;  48F634B7DC93354E CRC64;
     MSRQEIDYEK VAKVAESIKK RGIEPSLTDV CKELGIMNIT PKLTEFLEQW YHNQPEFKRK
     INAPLTENIK IEASNIVEKN IELEKSLSLL RATLESTADG IMMVNGKGQV VDWNQKFVDM
     WRIPPYMMEA GTERISFEYI LDQLIDPAAL ISDVQYLYQN PSWEGELPEL HFKDGRIFER
     FTQPQRVGNE IVGRVYSFRD VTQKRLAEDE LRIRDRAVEA STHGVVIIDV LKVEHPVIYI
     NKAFQKITGY TEKQALGKNL ASLLGRSSDD LNYKRLALAI KELREETVEV ESLRRDGEVF
     WCELSVAPVK DSFDQVRHYV CIVNDVTERR EMEKQLLRQA THDSLTELPN RVLLMDRVEQ
     AILQAKKKKS TLAFLFLDLD RFKMTNDTLG HGMGDKLLQV VANRLLIATD DYDTVARLGG
     DEFVVLLSEI PDHHEAEKKA REILSLVEKP VQIEQHSLKI TASIGISYYP RDGKDYESLM
     KTADLSMYHA KDSGRNTYRV FEQEMNRRII NTMQLDTALR DALKNNEFYL AYQPLIDLKN
     EKIVGVEALL RWKSKTLGQV APVDFIPMAE ENGQIIEIGV WVMEEACKQL KRWHNLGLKD
     LTMAVNISGR QFRQDKLFET VQKVLEKTEL EAKYLELEMT ETLLIEDIEH VVDAMHILKD
     MGVKLVIDDF GTGYSSLSYL KQFPVDKLKI DRSFINEMIS DDNDAAIAKA IINLGHSLNL
     EVLAEGIENE FQKNFVTANG CDYAQGYYFT APQKPENLLN FLVNFPNV
//