ID A0A0W0WUG5_9GAMM Unreviewed; 755 AA.
AC A0A0W0WUG5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATP binding protease component ClpA {ECO:0000313|EMBL:KTD35952.1};
GN ORFNames=Lnau_0936 {ECO:0000313|EMBL:KTD35952.1};
OS Legionella nautarum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=45070 {ECO:0000313|EMBL:KTD35952.1, ECO:0000313|Proteomes:UP000054725};
RN [1] {ECO:0000313|EMBL:KTD35952.1, ECO:0000313|Proteomes:UP000054725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49506 {ECO:0000313|EMBL:KTD35952.1,
RC ECO:0000313|Proteomes:UP000054725};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD35952.1}.
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DR EMBL; LNYO01000013; KTD35952.1; -; Genomic_DNA.
DR RefSeq; WP_058503983.1; NZ_LNYO01000013.1.
DR AlphaFoldDB; A0A0W0WUG5; -.
DR STRING; 45070.Lnau_0936; -.
DR PATRIC; fig|45070.6.peg.992; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000054725; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:KTD35952.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:KTD35952.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..145
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
SQ SEQUENCE 755 AA; 83644 MW; 90304E43A8CC503E CRC64;
MLNKELEFTL NLAFKEAKEK RHEFMTVEHL LLSLLDNPAA GNVLQACDAN VDSLRRDLLE
FIDETTPRIP EDELDRETQP TLGFQRVLQR AVFHVQSAGK TEVTGANVLA AIFSEQESQA
VYFLRRENIT RLDVINYISH GVSKYHNNEL NENMNSSMDE DSMGGEGNES PLESYCMNLN
KRARLGKIDP LIGRHEEIQR TIQVLCRRRK NNPLLVGEAG VGKTAIAEGL ARRIVDGEVP
EAISSCIVYS LDLGALLAGT KYRGDFEKRL KAVLKQLGQQ DGAVLFIDEI HTIIGAGAAS
GGVMDASNLI KPLLANGELK CIGSTTYQEY RGIFEKDRAL ARRFQKIDIK EPSIDETFEI
LKGLKGRLEE HHGVKFSIPA LKAAAELAAK YINDRFLPDK AIDVVDEAGA YQNLLTATKR
KKIISVTEIE SVVAKIARIP VKKVSARDKD TLRNLERDLK LLVYGQDDAI TALASAIKLA
RSGLRDAEKP VGCFLFAGPT GVGKTEVTKQ LANVLGIELL RFDMSEYMEK HTVSRLIGAP
PGYVGYDQGG LLTEAVTKNP HAVLLLDEIE KAHPDVFNLL LQIMDHGTLT DTNGRQADFR
HVIMVMTSNA GASEITRNSI GFSLQDNSND GLDAIKRQFS PEFRNRLDAI INFAPLDSVT
IGLVVDKFIM ELDEQLSNKG VTFKVDKAAR DWLIEHGYDK AMGARPMARL IQENVKKPLA
DELLFGKLSN GGHVTLKVKD GKLHFDSHDH REGVC
//
