ID A0A0W1A1D0_9GAMM Unreviewed; 629 AA.
AC A0A0W1A1D0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=IolC/IolB transferase kinase protein {ECO:0000313|EMBL:KTD75140.1};
GN Name=iolCB {ECO:0000313|EMBL:KTD75140.1};
GN ORFNames=Lwal_3181 {ECO:0000313|EMBL:KTD75140.1};
OS Legionella waltersii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=66969 {ECO:0000313|EMBL:KTD75140.1, ECO:0000313|Proteomes:UP000054729};
RN [1] {ECO:0000313|EMBL:KTD75140.1, ECO:0000313|Proteomes:UP000054729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51914 {ECO:0000313|EMBL:KTD75140.1,
RC ECO:0000313|Proteomes:UP000054729};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD75140.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LNZB01000060; KTD75140.1; -; Genomic_DNA.
DR RefSeq; WP_058481766.1; NZ_LT906442.1.
DR AlphaFoldDB; A0A0W1A1D0; -.
DR STRING; 66969.Lwal_3181; -.
DR PATRIC; fig|66969.6.peg.3469; -.
DR OrthoDB; 9792663at2; -.
DR Proteomes; UP000054729; Unassembled WGS sequence.
DR GO; GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01166; KdgK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR Gene3D; 2.20.150.10; putative 5-dehydro-2- deoxygluconokinase; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR021120; KduI/IolB_isomerase.
DR InterPro; IPR030830; Myo_inos_IolC.
DR InterPro; IPR023314; Myo_inos_IolC-like_sf.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR NCBIfam; TIGR04382; myo_inos_iolC_N; 1.
DR PANTHER; PTHR43085:SF49; 5-DEHYDRO-2-DEOXYGLUCONOKINASE; 1.
DR PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR Pfam; PF04962; KduI; 1.
DR Pfam; PF00294; PfkB; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Kinase {ECO:0000313|EMBL:KTD75140.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KTD75140.1}.
FT DOMAIN 16..325
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 629 AA; 71001 MW; 86F0F1D90D0DC06D CRC64;
MTYPVFYVDQ SRPIDLICMG RVAVDLYAEQ IGVDLSDVSS FKKYLGGCAG NIAVGTSRLG
LKSQLFSCVG TDDMGVFLQK ELCKERVNTD LLSTSDKHLT GLVLLGIAPP DRFPLIFYRK
DCSDMQLQNE HISDERLLHS KSLLITGTGI STQSMKNTTI QVVQRARRAE CAVIFDLDFR
PVLWGLTSVG NGENRYCQSE VVSKSYQEII PLCDLIVGTE EELCIAGGAN CLEQALATIQ
QLTNSPIVVK LGEKGAIIHF GSKHSVLKSQ PFPVEVLNVL GAGDAFMSGL LLGVLQGESW
EKSCQYANAC GAIVVTRHGC APAMPYKEEL EYFIAEYSKD PLIWSKTTFL QLHDSYNPSR
SKHALIKNPL GFSDGMNKIV SMHESFTGMN FSSLKLNKGE MYQFTQHYEF AALLLSGKVL
FDYSGHKKEA KRVDYFSQNP YVLHGSRAQQ CSVMALTDCE LLLIETDNER IFEPVLFDES
NMLELDERGK GILEDTSYRL VRTVFDKRNR PESNLVVGEI ITFQGRWSSY PSHYHDQPEI
YHYRFSEPQG YAFGESGKNV LRIEHYDTYQ IEKDQTHAHC TAPGYALYTL WFIKHLENNP
YGIPTFVKDH EWTRNTQANS RVFKRRKNP
//
