ID A0A0W1AAM0_9GAMM Unreviewed; 692 AA.
AC A0A0W1AAM0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:KTD78383.1};
GN ORFNames=Lwal_1818 {ECO:0000313|EMBL:KTD78383.1};
OS Legionella waltersii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=66969 {ECO:0000313|EMBL:KTD78383.1, ECO:0000313|Proteomes:UP000054729};
RN [1] {ECO:0000313|EMBL:KTD78383.1, ECO:0000313|Proteomes:UP000054729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51914 {ECO:0000313|EMBL:KTD78383.1,
RC ECO:0000313|Proteomes:UP000054729};
RA Burstein D., Amaro F., Zusman T., Lifshitz Z., Cohen O., Gilbert J.A.,
RA Pupko T., Shuman H.A., Segal G.;
RT "Genomic analysis of 38 Legionella species identifies large and diverse
RT effector repertoires.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTD78383.1}.
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DR EMBL; LNZB01000041; KTD78383.1; -; Genomic_DNA.
DR RefSeq; WP_058480474.1; NZ_LT906442.1.
DR AlphaFoldDB; A0A0W1AAM0; -.
DR STRING; 66969.Lwal_1818; -.
DR PATRIC; fig|66969.6.peg.1979; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000054729; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:KTD78383.1};
KW Cilium {ECO:0000313|EMBL:KTD78383.1};
KW Flagellum {ECO:0000313|EMBL:KTD78383.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000054729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 40..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 65..82
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 117..135
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 203..225
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 245..267
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 305..322
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 692 AA; 75397 MW; 833BC25CCDC1FAF9 CRC64;
MNNALYYLQF LMRQGFGTPL MLIVMISMMM LPLPPFLLDI FFTFNIALSL VVLLAVIYSE
RPLDFAVFPT VILIATLLRL ALNVASTRVV LLNGHQGTDA AGQVIKSFGE VVIGGNYTVG
IVVFIILVVI NFVVVTKGAG RVSEVSARFT LDALPGKQMA IDADLNAGLI NQEQAIKRRT
EVAQEADFYG SMDGASKFVR GDAIAGILVL IINIVGGLII GVFQFNMNLN DALHNYVLLT
VGDGLVAQVP SLLLSTAAAI IVTRVSSAQN MGQAVINQVL ANPRSLIIAS SIIGLIGIIP
GMPHIAFIIL SAGLAGIAYL FIRKEKEKKR TQEVTQTESI PTPDPAAAEL SWDDVNPVDV
ISLEVGYRLI PMVDSAQGGV LLARIKGVRK KISQELGFLI PTVHIRDNLD LKPNHYRLSL
AGVVMGEAAI HPDRWLAINP GQVFGDLDGI HDHDPAFGMD AIWIMENQKE QANTLGYTVV
DASTVIATHL SQILEQNSQQ LLGYEETQQL LDKLAVNSPK LVKELVPDNL PLGAVSKVLQ
GLLYEHIPLT DIRTIVETLA EFAPKSKDSD YLVSQVRIAL SRLITQKISG LHEELPIITL
KPELEQLLHN SIQNSGPSGI SFEPGMADKI QQSLIHFSQQ QQEKQESSVL VVQPGIRSVL
ARFVRTISND FHVLSYQEIP DNKQIRIVGT VG
//
