ID A0A0W1DUI2_9SPHN Unreviewed; 635 AA.
AC A0A0W1DUI2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:KTE21735.1};
GN ORFNames=ATE67_03495 {ECO:0000313|EMBL:KTE21735.1};
OS Sphingopyxis sp. H050.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=1759072 {ECO:0000313|EMBL:KTE21735.1, ECO:0000313|Proteomes:UP000053439};
RN [1] {ECO:0000313|Proteomes:UP000053439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H050 {ECO:0000313|Proteomes:UP000053439};
RA Gomez-Alvarez V., Revetta R.P.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTE21735.1}.
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DR EMBL; LNRZ01000002; KTE21735.1; -; Genomic_DNA.
DR RefSeq; WP_058815269.1; NZ_LNRZ01000002.1.
DR AlphaFoldDB; A0A0W1DUI2; -.
DR STRING; 1759072.ATE67_03495; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000053439; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 65..237
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 269..587
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 635 AA; 69346 MW; C30A08D301EE634B CRC64;
MPRKKSPPIT EAWRGFTFTR RALVVGGAQT AVGVALAARM TYISVVDNDR YVLESESNRV
NLTLVPPRRG WIVDRNGKAL ANNRVSLRID IIPDRLHNKD FVLGQLRTLL QLDGDTMERI
QRDLKSASGF QPVAVAEDMT EAEYSSILVR LPELPGVAPQ RGFARNYPTG AAVGHLIGYV
GAPTAEEYEK VKDPLYITPG FRTGKDGLEK YFQDMLRGKP GAKRVEVTAG GKVVRELETT
RDTQGKTVHL TIDADLQEFV ARRMGRESGA AVVIDCQNGD ILSFVSMPCF DPNSFSDGIS
SSEYSWLRED DHQPLINKAT RGLYPPGSTL KPMAAIAAIE HGIDPSERHT CIGGYRLGSR
FFRCLGRHGS VDMATAIMKS CNSYFYWVAH RLGYDAIAPT ARLMGLGEEF QLAGSNQRYG
TIPDSAWKMK KYDQPWSASD SLNAVIGQGY VSVNPLQLAV MAARIASGRR LYPRLVNRHF
RNEALPFSAE ALATARHGMD LVVNGPGGTA GRSKLPLDGI AMAGKTGTAQ VRGLNTGNGK
SGTWKFRDHG LFIGFAPVVN PRYATAVVIE HGMGGSRAAA PVAKDFMTFL FDRAKAMEAL
EAFEAGWGGT IKERMDRDYA AWKAGIARPD AGLAQ
//
