ID   A0A0W1R411_9EURY        Unreviewed;       809 AA.
AC   A0A0W1R411;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=AUR64_00595 {ECO:0000313|EMBL:KTG08110.1};
OS   Haloprofundus marisrubri.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloprofundus.
OX   NCBI_TaxID=1514971 {ECO:0000313|EMBL:KTG08110.1, ECO:0000313|Proteomes:UP000054387};
RN   [1] {ECO:0000313|EMBL:KTG08110.1, ECO:0000313|Proteomes:UP000054387}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB9 {ECO:0000313|EMBL:KTG08110.1,
RC   ECO:0000313|Proteomes:UP000054387};
RA   Zhang G., Stingl U., Rashid M.;
RT   "Haloprofundus marisrubri gen. nov., sp. nov., an extremely halophilic
RT   archaeon isolated from the Discovery deep brine-seawater interface in the
RT   Red Sea.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KTG08110.1}.
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DR   EMBL; LOPU01000034; KTG08110.1; -; Genomic_DNA.
DR   RefSeq; WP_058583192.1; NZ_LOPU01000034.1.
DR   AlphaFoldDB; A0A0W1R411; -.
DR   STRING; 1514971.AUR64_00595; -.
DR   OrthoDB; 8127at2157; -.
DR   Proteomes; UP000054387; Unassembled WGS sequence.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd00075; HATPase; 1.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR   PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR   Pfam; PF13185; GAF_2; 2.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SMART; SM00065; GAF; 2.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
FT   DOMAIN          591..784
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   REGION          157..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   809 AA;  87959 MW;  32BC1CA1CE7C813C CRC64;
     MASESSVRVL LVADAPVDRI DAVLDAETTF SVRRCGFDAV DAHLADVDCL VLTDARSLSG
     AARGIPTVLC TDSSAAAARP QRYDAFAPAD VPSTLPAQIR WATRRNDTAD RRRIAKLHEG
     AATLIAARSA EELYESTVDI ASRVLAFDTC YVGVVTDDPN STGTERGTAD GGTHTDGEEW
     VVPTAIQPAS AYVAELPVSH GVAGETYRTG ESLLIGDLQA NPVAEPSDPD YRSGISLTLG
     DGAVFQAIST QVNAFDETDL HLAELLVTYA TETLSRIRSE EALRQRREEI ARLHEATTEL
     VGCADEDELY RRAIETAENV LSFDSCYVRM VEDGQFVVRA ETNRSSPWTL GSIPVGHGIT
     GKTLSEGRSF LIEDVQRDTR ADPVDNGFRA ALSIPMGDAG VFQALSATPA AFDERDLEFA
     EILVSYVRTT RSRIRSERAL RTRERELTAE RDRLGALFEN VPDAAVAYEF VDGEPIVRRV
     NSAFEEVFGY DADTIVGENV DEYIVADGDD GDDPSSAPRL NRQLQDGESL RRECRRLTAD
     GPREFLLHVV PLAIGETNVA GFAIYTDITE RTLREKRLAR QNEQLEEFAH IVSHDLRNPL
     SVAVGHLSLA RETGSEESFE AVERSLDRMD DLIDDLLSLA RAGRTVEERT PLDATEVATR
     AWAGVDTADA TIRREGSIPV DADESRLREL FENLFRNAIE HGGETVSVTV GPVDDGFFVA
     DDGPGVAEAD RERVFERGFS TGGDGIGVGL HIVRTIAEAH DWSVTVCDSP EGGACFHFVT
     DETTDPADAE AVELSDDSFP TLGNASKEE
//