ID A0A0W7WPW8_9RHOB Unreviewed; 647 AA.
AC A0A0W7WPW8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:KUF12638.1};
GN ORFNames=AVJ23_02665 {ECO:0000313|EMBL:KUF12638.1};
OS Pseudoponticoccus marisrubri.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Pseudoponticoccus.
OX NCBI_TaxID=1685382 {ECO:0000313|EMBL:KUF12638.1, ECO:0000313|Proteomes:UP000054396};
RN [1] {ECO:0000313|EMBL:KUF12638.1, ECO:0000313|Proteomes:UP000054396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJ5A-1 {ECO:0000313|EMBL:KUF12638.1,
RC ECO:0000313|Proteomes:UP000054396};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF12638.1}.
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DR EMBL; LPXO01000001; KUF12638.1; -; Genomic_DNA.
DR RefSeq; WP_058860582.1; NZ_LPXO01000001.1.
DR AlphaFoldDB; A0A0W7WPW8; -.
DR STRING; 1685382.AVJ23_02665; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000054396; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054396};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..236
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 269..602
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 610..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..647
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 647 AA; 71575 MW; 04AAACCA0104D358 CRC64;
MRRTSRENAE SARRITRRGL ILGGAQVGFA GLLALRMRYM QVDQADEFRL LAEENRISIR
LIPPSRGRIF DREGRIIAEN EQTYRITLVR EDAGDVNDVI ARLGQLIELD EDDLNRALTE
MQRTAPFHPV TVADRVSWED LSRVAVNAPA LPGVVPEVGL SRFYPERELY AHVAGYVGPV
SERDLERYED PPAVLRIPRF QIGKVGVEAK HEEVLRGSAG AKRVEVNSVG RVMRELDRRE
GVAGTDLQLT VDNALQSYVQ ARLGQESASV VVMDVEKGDL LAIASAPSYD PNKFVRGISV
ADYGELRDND HRPLASKTVQ DAYPPGSTFK MVTALAALDA GLVSPEETVW CPGHLEVGGR
RFHCWKRVGH GHMNLEQSLR ESCDVYYYEL ALKVGIERIA AMARKLGLGE AYDVPMSAVT
KGLIPDKEWK RRERQAEWVI GDSVNASIGQ GFVLSSPLQL AVMSARLATG RSVTPRLVKS
IDGVETPHTG GSDLGFNPNH LLQIRRAMYA VSNNRRGTAY RSRIVAEGMR MAGKTGTSQV
RNITAAERAR GVTSNADLPW ERRDHALYVN YAPWDNPRIA VSVVVEHGGG GSTAAAPIAR
DVTLQALFGG DPPLDAYPRS EQRKVKAQQE RLAREREERR AEGDSRA
//
