ID   A0A0W7WYC2_9ACTN        Unreviewed;       353 AA.
AC   A0A0W7WYC2;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=NADH-ubiquinone oxidoreductase {ECO:0000313|EMBL:KUF15570.1};
GN   ORFNames=AT728_26370 {ECO:0000313|EMBL:KUF15570.1};
OS   Streptomyces silvensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF15570.1, ECO:0000313|Proteomes:UP000054804};
RN   [1] {ECO:0000313|EMBL:KUF15570.1, ECO:0000313|Proteomes:UP000054804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF15570.1,
RC   ECO:0000313|Proteomes:UP000054804};
RA   Johnston C.W., Li Y., Magarvey N.A.;
RT   "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT   novel hormone antagonists.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUF15570.1}.
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DR   EMBL; LOCL01000044; KUF15570.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0W7WYC2; -.
DR   STRING; 1765722.AT728_26370; -.
DR   OrthoDB; 8650434at2; -.
DR   Proteomes; UP000054804; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 1.10.1040.20; ProC-like, C-terminal domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR018931; DUF2520.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR019665; OxRdtase/DH_put_Rossmann_dom.
DR   InterPro; IPR037108; TM1727-like_C_sf.
DR   PANTHER; PTHR40459; CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN; 1.
DR   PANTHER; PTHR40459:SF1; CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN; 1.
DR   Pfam; PF10728; DUF2520; 1.
DR   Pfam; PF10727; Rossmann-like; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW   Ubiquinone {ECO:0000313|EMBL:KUF15570.1}.
FT   DOMAIN          16..140
FT                   /note="Putative oxidoreductase/dehydrogenase Rossmann-like"
FT                   /evidence="ECO:0000259|Pfam:PF10727"
FT   DOMAIN          157..282
FT                   /note="DUF2520"
FT                   /evidence="ECO:0000259|Pfam:PF10728"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          311..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   353 AA;  35435 MW;  B758AEAC449143EF CRC64;
     MNASHGPEQQ PEARSDPRNR PARLSVGVVG AGRVGPALAA SLQLAGHRPV AASGVSESSR
     RRAALLLPDV PLVSPSQVLE RADLVLLTVP DDALPGLVEG LAETGAVRPG QLLVHTSGRY
     GTKVLDPALR AGALPLALHP AMTFTGTPVD VQRLAGCSFG VTAPEELRLA AEALVIEMGG
     EPEWIAEEAR PLYHAALALG ANHLVTLVAE AMELLRDAGV NAPDRMLGPL LGAALDNALR
     SGDAALTGPV ARGDAGTVAA HVAELRKHAP GTVAGYLAMA RATADRALAH GLLKPELAED
     LLGVLAGGVP GPGGPGGFRD GGPGGFPDGG PGGLGDGGPD GPRGSGPDGG EQR
//