ID A0A0W7WZ75_9ACTN Unreviewed; 487 AA.
AC A0A0W7WZ75;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:KUF15848.1};
GN ORFNames=AT728_14175 {ECO:0000313|EMBL:KUF15848.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF15848.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF15848.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF15848.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF15848.1}.
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DR EMBL; LOCL01000042; KUF15848.1; -; Genomic_DNA.
DR RefSeq; WP_058850080.1; NZ_LOCL01000042.1.
DR AlphaFoldDB; A0A0W7WZ75; -.
DR STRING; 1765722.AT728_14175; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 157..480
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 487 AA; 52712 MW; DFD5B840C90933CC CRC64;
MNKPLRRIAI FCGLLVLALL VRDNWLQYVK ADNLAEHEMN RRVPIERYAQ PRGDIIVDGK
AVTGSKKVDG GDFKYKRTYK DGPMWSPVTG FASQRIGATQ IESIEDGILT GKDDRLFFRR
SLDMLTGKKK EGGNVVTTLN RDAQKAAYDG LKSKGKGAVA AIDPSTGAIL ALASTPSYDP
SSFAGNFNKD AETFGKLDKD PDKPMLNRAL RETYPPGSTF KVVTAAAAME HDLYTDIDGK
TDSPLPWTMP DTSTPLKNEG NIPCKNATLR EALRVSCNTV FGKIGSDLGK DKMLETAEKF
GFNEEQFVPV RSNASTFPKE MDRPQTALSS IGQFETAATP LQMAMVTSAI ANDGTLMEPY
MVKELQAPNL DVIEKHSPKE MSEPLSKENA QKLQDMMQTV VNEGTGTRAK IPGVTVGGKT
GTAQHGLNNS KNPYAWFISY AKTDSGSPVA VAVVVEDSGA SRDDISGGGL AAPIARDVMK
AVLDSKK
//
