ID A0A0W7X611_9ACTN Unreviewed; 976 AA.
AC A0A0W7X611;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN ORFNames=AT728_24705 {ECO:0000313|EMBL:KUF18183.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF18183.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF18183.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF18183.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF18183.1}.
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DR EMBL; LOCL01000031; KUF18183.1; -; Genomic_DNA.
DR RefSeq; WP_058847555.1; NZ_LOCL01000031.1.
DR AlphaFoldDB; A0A0W7X611; -.
DR STRING; 1765722.AT728_24705; -.
DR OrthoDB; 7053960at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 898..963
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 976 AA; 102571 MW; 73598535BDB5B167 CRC64;
MSEGRTTGAG AGPGAPELTG RATQRAVIDA ALAGIATSGA SVILRGDPGT GRTALLGAAE
ATARRAGLRV LRMTGAEAES ELPFAALHQV LWPLLDDSDG LSAPQRHALE SALGVREGTP
PEGFTVAGAA LTLLAHAAAR RPLVVLLDDL QWADPSSVAV FGYVQRHLAP LPLVAIAATR
RTGTATGRDR AADRAADRAE HDTAACLAGQ VIDLPPLDEP QAELLLRTRH PSLPAGARRR
VLRAAAGNPL ALHELAEQVG RLAAHRAEAL ASPAPPEMPE LFDALPLGER LGRLYEDRLR
ALPAAVRGLL LVAALGDAAT RHRTVLRSLA EHAAGPPWHR LEEHIERSGL AHLDPEREVL
EFHHALVRAC LAHLATPAEL RAAHRRLADA LPAEDARRTL HLAAAALGPE AGLAARLHAE
ADSMSAQGGE AEAAVVMARA AGLSPDRTSR TARLVAAAAL AVQAGRPHLA AEHLADAEAA
ARPGRPEPAA PYAFAVACAR LQLDADPRPA VELLPAVLDA PVPPDAADQH AALVGPILFL
LLVAAALTGD ERAWAAVDRH AAHPDAPPAA ELCRQAWSGP RPAVRAVHEL PRRLRETVAA
LPADRETTDA WLLLWTAAAV DSLGEHCALW SAFARRHAYA TQTFTDSLRA HDDFLHGNWD
SALAAARAGA RTSAEHGYAL AETLFLKTAG QILAARGDRA GLAALAPVLG TRAGERRLRL
VTDLLSGMLT LCALGRGDAE EAWLHACDLT APGAVADRGP WTHLSLVDRV QAAVDSGRAE
EARRHLRAVG ASGLARISAH HTFLVTVAEA VAAADDEADE RHAAVYARPD AENWPFPLAR
AHLAHAVRLR RQHRPEEASA HCRAALTVFT RLGATPWAAR ASRELAANDA DIAAASGTAG
HHPLLTAQET RIARLAARGL TNRQIGARLS LSPRTIGAHL YRIFPKLGVT TRAGIARALE
ASLRNAAAPP QEPPAT
//
