ID A0A0W7X8D4_9ACTN Unreviewed; 995 AA.
AC A0A0W7X8D4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=AT728_21675 {ECO:0000313|EMBL:KUF19173.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF19173.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF19173.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF19173.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF19173.1}.
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DR EMBL; LOCL01000028; KUF19173.1; -; Genomic_DNA.
DR RefSeq; WP_058846663.1; NZ_LOCL01000028.1.
DR AlphaFoldDB; A0A0W7X8D4; -.
DR STRING; 1765722.AT728_21675; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022827};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804}.
FT DOMAIN 913..988
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 494..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 995 AA; 104510 MW; 4E83E9146D04EDB0 CRC64;
MPHATGWQRH LVRDFTHSMA AAGLAPSPAG AHDALTRGGW HAACLPADAG GLGLTWYEAA
MLAERAGRVL APTQALDTLL ALPALTAAAP RAAAAVLAGT RTPGLVTPAQ LRASRVSSGE
AAAYRFTAGP PGLVLLPAPD APAEVACVEV AAGDGVRVAT PGDELWQMRA GRPGRRSPEV
FRTPAGALWA ATALLRNAHL AGVCLAAVET AVDRLRSRRQ FGRPLAAQQA LVHPLAAHRA
RLEALRLEND AQLLKLDECA GQPTLGRARH YADVEADAAT VGGVLWSLLR ECVRHAVHVH
GASGLQDGQP VALAHRLVLT ETARLGPDAR QPAWNTGAPT AKEPALLRGI GRLRTPSPRH
LAQRREPALV REARTDAPTG PCAHEMFARA AARHPEAVAV RTATQELTYR QLNADADRLA
DALGGRGIGR DDVVGLHMGY GADTVTAILG VLKAGAAYLP LDPGYPAERL AFVIQDSRAA
AVLTDDRQAA SVLTGSGQGA AGRTGSGQAG AGPAGTVPVW TAAELLSRAA ERPLPARVPG
ARPDSLAYLI YTSGSTGTPK GVEVEHRGLA NRLRWDAAAF PLGPGDAVLQ HTSLSFDISV
WEVFAPLMSG ATLVVAAPGA SSDPRRLLRD MRRDQVSVLA CVPSLLDLLV AEREPGLADV
GGLRYVFCGG ETLSPELCRR FHALGLSAQL HNFYGPSECT IDVTSWHCRP QQDDAPVPIG
RPLDNVTVHV FDETGALVPP GYPGELYVGG AGVARGYRNR PGLTAERFVA DPFSGRPDAR
LYRTGDLVRM GRDGVVHFLG RSDGQVKVSG HRIELDEIRC TLERHPGVRT AVVQVRQERI
EAHVVPVGPP EAAPGIEELV DHARLSLPAY MVPAALATVA TLPVTRNGKI DHRALPPLRT
PRPAPAGDAD AAGAGNAEEQ ALAALAARVL GLDTLGPGDD FFAAGGSSLH AARFVSRVRS
ERGLDIRLEQ FLAAPTVREL ARAASPRAGR GEESA
//
