ID A0A0W7XAE8_9ACTN Unreviewed; 442 AA.
AC A0A0W7XAE8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cyclopropane-fatty-acyl-phospholipid synthase {ECO:0000313|EMBL:KUF19900.1};
GN ORFNames=AT728_03670 {ECO:0000313|EMBL:KUF19900.1};
OS Streptomyces silvensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1765722 {ECO:0000313|EMBL:KUF19900.1, ECO:0000313|Proteomes:UP000054804};
RN [1] {ECO:0000313|EMBL:KUF19900.1, ECO:0000313|Proteomes:UP000054804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53525 {ECO:0000313|EMBL:KUF19900.1,
RC ECO:0000313|Proteomes:UP000054804};
RA Johnston C.W., Li Y., Magarvey N.A.;
RT "Draft genome sequence of Streptomyces silvensis ATCC 53525, a producer of
RT novel hormone antagonists.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF19900.1}.
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DR EMBL; LOCL01000026; KUF19900.1; -; Genomic_DNA.
DR RefSeq; WP_058846397.1; NZ_LOCL01000026.1.
DR AlphaFoldDB; A0A0W7XAE8; -.
DR STRING; 1765722.AT728_03670; -.
DR OrthoDB; 9782855at2; -.
DR Proteomes; UP000054804; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003333; CMAS.
DR InterPro; IPR020803; PKS_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43667; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR PANTHER; PTHR43667:SF1; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR Pfam; PF02353; CMAS; 1.
DR PIRSF; PIRSF003085; CMAS; 1.
DR SMART; SM00828; PKS_MT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000054804};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 157..398
FT /note="Polyketide synthase methyltransferase"
FT /evidence="ECO:0000259|SMART:SM00828"
FT REGION 124..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 49519 MW; B2E923CE958F8DA2 CRC64;
MQDAAVRLKN LAEQLTGAEL PIRVRAWDGS EAGPPGAPTL VVRHRRALRR LLWKPGELGL
ARAWVAGDID VDGDLYVVLD LLAEYIWERG EDARTLADNL RDPEVRSAAR SLFRLAAPFV
PPPAPREEMR RQSRLHRHTR GSDKKAVSHH YDVGNDFYEL VLGPSMVYSC AYWESPDATL
EDAQRDKLEL ISRKLGLRPG MRLLDVGCGW GSMAVHAARE HGVSVVGVTL SQEQAAYARK
RIAQEGLTDR IEIRVQDYRD VRDGPYDAIS SIGMAEHVGA DRYLEYANDL RALLKPGGRL
LNHQIARRPQ ADESAYTVDE FIDAYVFPDG ELAPLGTTVG LLERAGFEVR DVESIREHYA
LTLRRWVANL EAHWPEGVRL TSPGRARIWR LYMAASALAF EHNRIGVNQV LAIRTPEEGT
SGLPLRTRQW REGFGDFSPS GV
//
