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Database: UniProt
Entry: A0A0W7YTB9_9BURK
LinkDB: A0A0W7YTB9_9BURK
Original site: A0A0W7YTB9_9BURK 
ID   A0A0W7YTB9_9BURK        Unreviewed;       468 AA.
AC   A0A0W7YTB9;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-SEP-2017, entry version 14.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AS359_11640 {ECO:0000313|EMBL:KUF38374.1};
OS   Acidovorax sp. 12322-1.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Acidovorax.
OX   NCBI_TaxID=1705602 {ECO:0000313|EMBL:KUF38374.1, ECO:0000313|Proteomes:UP000053300};
RN   [1] {ECO:0000313|EMBL:KUF38374.1, ECO:0000313|Proteomes:UP000053300}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12322-1 {ECO:0000313|EMBL:KUF38374.1,
RC   ECO:0000313|Proteomes:UP000053300};
RA   Ming D., Wang M., Hu S., Zhou Y., Jiang T.;
RT   "Complete genome sequence of a multi-drug resistant strain Acidovorax
RT   sp. 12322-1.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KUF38374.1}.
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DR   EMBL; LPXH01000040; KUF38374.1; -; Genomic_DNA.
DR   RefSeq; WP_058880515.1; NZ_LPXH01000040.1.
DR   EnsemblBacteria; KUF38374; KUF38374; AS359_11640.
DR   Proteomes; UP000053300; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053300};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053300}.
FT   DOMAIN      165    299       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      376    445       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     173    180       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   468 AA;  52922 MW;  8365CDB6676DD15D CRC64;
     MTEELTNDAG LGLWLACVEQ LSQDLPEQQF NTWIKPLTAV VAEDFSKVTV YVANRFKLDW
     IRAQYAARIA GLLEDLYGQP VILELALAQR EGVTRTYVRP YQAERSTPAE VPTLLPANAA
     PEESAAPAFR TRLNSALTFE TLVEGTANRM ARSAAMHVAA SPGHLYNPLF IYGGVGLGKT
     HLVHAVGNKL LEDRPDAKVL YIHAEQFVSD VVKAYQRRTF DEFKERYHSL DLLLIDDVQF
     FANKDRTQEE FFNAFEALLA KKSHIVMTSD TYPKGLTNIH ERLVSRFDSG LTVAIEPPEL
     EMRVAILINK ARAENAEMPE EVAFFVAKNV RSNVRELEGA LRKILAYSRF NQKEISIQLA
     REALRDLLSI QNRQISVENI QKTVADYYKI KVADMYSKKR PASIARPRQI AMYLAKELTQ
     KSLPEIGELF GGRDHTTVLH AVRKIAAERQ QQTELNQQLH VLEQTLKG
//
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