ID A0A0W8B4P6_PHYNI Unreviewed; 1643 AA.
AC A0A0W8B4P6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Abnormal spindle microcephaly-associated protein {ECO:0000313|EMBL:KUF66914.1};
GN ORFNames=AM587_10016180 {ECO:0000313|EMBL:KUF66914.1};
OS Phytophthora nicotianae (Buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF66914.1, ECO:0000313|Proteomes:UP000052943};
RN [1] {ECO:0000313|EMBL:KUF66914.1, ECO:0000313|Proteomes:UP000052943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT "Genomes and virulence difference between two physiological races of
RT Phytophthora nicotianae.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUF66914.1}.
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DR EMBL; LNFO01006082; KUF66914.1; -; Genomic_DNA.
DR STRING; 4790.A0A0W8B4P6; -.
DR EnsemblProtists; KUF66914; KUF66914; AM587_10016180.
DR OMA; RYFGTTW; -.
DR Proteomes; UP000052943; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR CDD; cd00201; WW; 2.
DR Gene3D; 1.10.287.2900; -; 1.
DR Gene3D; 1.20.5.190; -; 5.
DR Gene3D; 2.20.70.10; -; 2.
DR InterPro; IPR012891; GCK_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR Pfam; PF07802; GCK; 1.
DR Pfam; PF00612; IQ; 10.
DR Pfam; PF00397; WW; 1.
DR SMART; SM01227; GCK; 1.
DR SMART; SM00015; IQ; 19.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50096; IQ; 15.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000052943};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1643
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006939741"
FT DOMAIN 1444..1478
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 1494..1522
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 298..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1310..1373
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 367..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1643 AA; 189289 MW; 336C94E53CD6C17B CRC64;
MSTTFLRTRR LLPFLAAPTA LLSVSSAHLE AAEPEPEATP PSHPAVDFVG VFVEKESAAR
LRKQFPAKFG SADEPLVVVL RFQPTVEEQE AFAPILGRAA KLHVKGLAED DHAQTVLVAV
TTETGESLEY EGAAEPAHAT LSTSAGGLSA GYSSVLLERL RASDKLRYLL DDEEDTNEWT
GELPAFESKH LPLFSPFPAV EAKIVKVDAK HSEQLALQGT VCLSSRFDVA TGKCQAPKAE
CGFCKFMKAG PCGKEFTAWE ACLDRCKKSG DDFIEKCGAQ TLALRDCVDA NPEYYHVLND
GPDEEKPDEE TEVKAEAEEN HIVTSLLRPL ATLDRLKSID AVPVSSWDKE AATRRPQLVQ
LPSGPVSAPK KLQQQQQQHA SPNQRSATPL QPLPKTSGIR LNRSTKRVTK VPKLSFTKRR
GRNAISNQFS LDGARQVNAG VYLLENVNTG HRYFGTTWDL QNAAAQSFHD LQLGVHPHQA
LSTCFILYGE AASGIRFRVL EQVSPPSSPK PPVYTDQVRA KRRRIKRLLA GREADNNEDG
FDVRAMERKL ATRLRFHHRK VIRRAAYKIV RRFLVMPILA RAWPLWVRAA EGCALVERTA
ATVEIQRVAR GYLDRVMVDK IRRDRAARTL LRFMRRCHFT LACRRRARSR LESKAARVLQ
RSMREFVARR KARRRRDGVR RWLAARKLQT HVRRHLARRL VDRMRLDKRR ARAAVDMQRT
TRGHLARLRV QRQRQRRIDD KAATDIQKIW RGYSTRTKVT LRSLGALSTH RLHHCSIDEL
RDEAARTIQQ AYSRWEARRL REQNEKATTI RLAYRNYVAR KFGWAAVTVM LETAMANRIQ
RAGRRWMFQR KLRRVVNEFR RDKAALTIQC CTRQHHARLK LYRLRKKKKC AQAIRQIQAF
WRGCWMLLNL LERILKRKRE RAAKRIQATY RAWIARREYV AIRDLARRNR AATKMQCMFR
ARQARRELMR RQVVRRLGAC ESCRSQLATV YHFEAESELC AACSDEFASL GDAVMETIDV
TVYRRILVPL MSAQRAYRAF QTQMRLRFGT CTLCEKHAVR RSCWSCLYGQ GFTANVGKRN
GKPAMGLTFC RSCDALFHER KQHQRKDIEL AYTEDAAAVT IQKYYRRFAQ RCTVADLRLA
QQTLAAKRVQ VCFRRHRQRR ITRAICAAHR RQQVLEAGAA LTIQRAVRGY LARCELLHLK
YERDSAIKIQ RAFRRYQARR VYNAAVVIQS HVRGWLARRV ACILRQERQG RQQNAAACCI
QRHVRGFLAR RRVWHLRQHK AAVRIQSAWR GYVARCELHA LQLEKQRRFN EELRTRLSAV
AAQIAECERA AATCIQTEVR GRQARIELYR RKLQAARSAR EQLRDNAVAL EAASATCIQR
HVRERLTAPV SHHRLRAQCC ARCFLSRRTV KRMRLEKQSA VRIQRAFRYS RAKRRLARLV
DDDTTPASAW VELFDEASGC VYYYHTETGE SVWERPAEMD TSPEDATSEN VGEWVEYWDE
NVGTSYFYNV KTGEATWATP AGYQSSNLED TTTAETWPLN NGGSYYTLQP RSKLESKDAE
NQKTEVYGDQ YAPYGYEDQA YYDNNHEEGA YYYYGDGTAY AYPDDEPVDT EYDINYKIYL
TQIAQEQQQQ QQQDQKPNDT KQA
//
