ID   A0A0W8DDT3_PHYNI        Unreviewed;       987 AA.
AC   A0A0W8DDT3;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   03-MAY-2023, entry version 22.
DE   SubName: Full=Pleckstrin y domain-containing family M member 2 {ECO:0000313|EMBL:KUF94515.1};
GN   ORFNames=AM587_10007179 {ECO:0000313|EMBL:KUF94515.1};
OS   Phytophthora nicotianae (Buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4790 {ECO:0000313|EMBL:KUF94515.1, ECO:0000313|Proteomes:UP000052943};
RN   [1] {ECO:0000313|EMBL:KUF94515.1, ECO:0000313|Proteomes:UP000052943}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=race 0 {ECO:0000313|Proteomes:UP000052943};
RA   Liu H., Ma X., Yu H., Fang D., Li Y., Wang X., Wang W., Dong Y., Xiao B.;
RT   "Genomes and virulence difference between two physiological races of
RT   Phytophthora nicotianae.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUF94515.1}.
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DR   EMBL; LNFO01001151; KUF94515.1; -; Genomic_DNA.
DR   EnsemblProtists; KUF94515; KUF94515; AM587_10007179.
DR   OMA; QYLWELP; -.
DR   Proteomes; UP000052943; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd00159; RhoGAP; 1.
DR   CDD; cd17671; RUN; 1.
DR   Gene3D; 1.20.58.900; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR006816; ELMO_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR004012; Run_dom.
DR   InterPro; IPR037213; Run_dom_sf.
DR   PANTHER; PTHR12771:SF56; CED-12; 1.
DR   PANTHER; PTHR12771; ENGULFMENT AND CELL MOTILITY; 1.
DR   Pfam; PF04727; ELMO_CED12; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF02759; RUN; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SMART; SM00593; RUN; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF140741; RUN domain-like; 1.
DR   PROSITE; PS51335; ELMO; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS50826; RUN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000052943}.
FT   DOMAIN          109..293
FT                   /note="RUN"
FT                   /evidence="ECO:0000259|PROSITE:PS50826"
FT   DOMAIN          420..617
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   DOMAIN          697..905
FT                   /note="ELMO"
FT                   /evidence="ECO:0000259|PROSITE:PS51335"
FT   REGION          66..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          933..987
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        933..966
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   987 AA;  110705 MW;  5941482755D6B841 CRC64;
     MEFFARLGNF VLGEPEEETE EEQQLRRRNR AKRQLQAKSK RGIILEDLES AVKGLQLFMD
     AKKGTSNNNC RSSSMDDGSD TTSMSNDDND SPKAAMMEST DDARELLLND EQAVVNLLCT
     QLDRCISHGL RLLEADESSS GATVKFFGVV KWTCTRMEAI RQKQMVEAMH RAAAAPKGPT
     SSTNSKVCEV VTSSVEADLP RHVRGLVGAV RSAIGLTNVH TDEGKARAFI RQALNTHVLQ
     SSLSMVLSET NLDLLASYYT EFALFRQRDE VKMFLNLLSG LDNLPFAFLI DDPRLDLAPE
     TLPFSRPLPR PKARKSKKQA PKLIDPEDMV SGRVRLCQAD DETDMLAEKL VSHHELRLAF
     NSRKGGNPLS ETLRQAAQSQ KMEDAATAVL RFLELGYPEY DVFGSDLLDV LCNPFLSGMA
     RFETALGLPD VAEACFCYLY EHVDSPGLFQ AHLQASHVME LRDTIEELGG FHRKMAVDPH
     EVVAILLQYL WELPDPLLTE ERLDRFLVCA GRPGSGMSEE ECKAVLVVLV NDLPWYCKPL
     LERLCHWVSV ALQPRHAEKN GLTVYAIANC LAPLLLRGRH SERFHDFEDS SYRKYPVGYQ
     HRTSVRSRLM PDEEDYLSTF PGNSLGLPSD AREVRHKTRD AEEAVQVIAM LFREQEAVLR
     DFRAELCSRR SQLRDKVRRL ETLRFGMEDP LDMTNESHVA LLXRLWDALL VPENEESDSV
     LSASSNSESE VGGVDVAAML ASPRWKCSGF HTDNPLGGFR GGGVLALEXL VYFLEEYPEK
     ARAMMERNAV AGGNRYPFPV ASINVMRMMM HLLMLDEAPD VCTKLVLHSV ETNDDTSPAV
     VMKLRVAERV SRTPFWRVFD DQKAFFKLHA MAFMLLDLHW VHSGATQMGF QPVLDATRRQ
     MGWLLEQAPI SVEEMWTTWM KVRELDATKF TGPTNFDSSA MTSPTSSASS ALENERVAQQ
     MTRNLSTKVE DDAEQPQEGT SATPAAG
//