ID A0A0X3SE00_9ACTN Unreviewed; 746 AA.
AC A0A0X3SE00;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ADL25_18935 {ECO:0000313|EMBL:KUJ40181.1};
OS Streptomyces sp. NRRL F-5122.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609098 {ECO:0000313|EMBL:KUJ40181.1, ECO:0000313|Proteomes:UP000054048};
RN [1] {ECO:0000313|Proteomes:UP000054048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-5122 {ECO:0000313|Proteomes:UP000054048};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUJ40181.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMWH01000183; KUJ40181.1; -; Genomic_DNA.
DR RefSeq; WP_059128950.1; NZ_LMWH01000183.1.
DR AlphaFoldDB; A0A0X3SE00; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000054048; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054048};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 172..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 196..326
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 724..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 746 AA; 77745 MW; DCA6F7812516315C CRC64;
MADLARWCVR HRLVTVVLWL VALAGVTTAS TVAGTAYSSD YGIPGTESHR AAGLLERGFP
GLGGDSDTVV WQTGAEGVRA ADVEQTMTRT LDHIADLHGV AAVTSPYKDG HSDQISRDGR
MAYATITFER SAEDIGKGEA KAVVDAAESA ETDGLKVELG GSAVGATEAK GGHLAEIVGV
AVAALVLFLA FGSPAASLLP IATALTGVGT AYAGIGLLGH AMTVADFAPM LGMLIGLGVG
IDYALFIVTR HRRSLKRGVP ADEAAAGAVA TTGRAVVFAG ATVCIALLGM LILRLGFLNG
VAIAASLTVL LTVAASVTLL PALLSFIGPR ALSRRERRRL QEHGPGPEVP TGLSARWSAF
VERHPKKLGV VALAVMALLA LPTLSLHLGT SDQGNDPKAS TTRQAYDLMA EGFGPGVNGP
LTLVTQVRGA EDKLALDNLD SALEATPGVA SVTPATYNSG GDTAYLTVVP DSAPQSQQTS
ELVKRLRSEV LPRAEQGTDL DVHVGGITAV YDDFANVIVG KLPLFVGVVI GLGCVLLLLA
FRSLAIPLKA AVMNVAAVAA AFGVVVAIFQ WGWGSELLGL GRAGPIEPFL PVIMVSVLFG
LSMDYQVFLV SRMYEEWLET GDNRRAVRVG LAETGRVINS AAVIMISVFL AFVLSGDRVI
AMFGIGLASA VALDAFVLRT LLVPALMHLL GGANWWLPTW LDRRLPRLCI EPAECRATIP
EQRAGEAVPA GAGAKEQHED VRDIPG
//
