ID A0A0X3VLH2_9ACTN Unreviewed; 332 AA.
AC A0A0X3VLH2;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=DUF218 domain-containing protein {ECO:0000259|Pfam:PF02698};
GN ORFNames=ADL12_03660 {ECO:0000313|EMBL:KUL45444.1};
OS Streptomyces regalis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68262 {ECO:0000313|EMBL:KUL45444.1, ECO:0000313|Proteomes:UP000053923};
RN [1] {ECO:0000313|Proteomes:UP000053923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3151 {ECO:0000313|Proteomes:UP000053923};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL45444.1}.
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DR EMBL; LLZG01000013; KUL45444.1; -; Genomic_DNA.
DR RefSeq; WP_062698391.1; NZ_LLZG01000013.1.
DR AlphaFoldDB; A0A0X3VLH2; -.
DR OrthoDB; 9782395at2; -.
DR Proteomes; UP000053923; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd06259; YdcF-like; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR003848; DUF218.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR PANTHER; PTHR30336:SF18; MEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF02698; DUF218; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053923};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 159..306
FT /note="DUF218"
FT /evidence="ECO:0000259|Pfam:PF02698"
SQ SEQUENCE 332 AA; 36556 MW; 17CAE5866BE71B3B CRC64;
MIIFAPAGVF FLVFACSFLY DRRLVRNGVY LFFALLSLSL GLLYKLASAS ETAPLVLLLT
LWILLMLLPF VLAVFLIANG VTMLRREGRS LANLLSLAAG GGILLFIALK AIANSTRWEL
LGTPLDAVGF VLGYVSLLFV CFLLYSFVYG RIRHRCAVDF VVVLGSGLIG GSRVPPLLAG
RLDRGRAAFD ARRAEGRETM LLTSGGQGPD EDLPEARAMA DYLITAGVPA DRILIEDKSR
TTQENLRFSK ALMQDRKTDY RALVVTNNFH VMRAAQIARK EKVEAQVIGA PTARYFWPSA
TIREFVALFL SHRILNLGIC ALLAVIGLLH LY
//
