ID A0A0X3W3A3_9ACTN Unreviewed; 423 AA.
AC A0A0X3W3A3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KUL51480.1};
GN ORFNames=ADL30_27295 {ECO:0000313|EMBL:KUL51480.1};
OS Streptomyces sp. NRRL S-1521.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609100 {ECO:0000313|EMBL:KUL51480.1, ECO:0000313|Proteomes:UP000053420};
RN [1] {ECO:0000313|EMBL:KUL51480.1, ECO:0000313|Proteomes:UP000053420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-1521 {ECO:0000313|EMBL:KUL51480.1,
RC ECO:0000313|Proteomes:UP000053420};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KUL51480.1}.
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DR EMBL; LLZK01000229; KUL51480.1; -; Genomic_DNA.
DR RefSeq; WP_062780147.1; NZ_LLZK01000229.1.
DR AlphaFoldDB; A0A0X3W3A3; -.
DR Proteomes; UP000053420; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR025828; Put_sensor_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF13796; Sensor; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KUL51480.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053420};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 7..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..200
FT /note="Putative sensor"
FT /evidence="ECO:0000259|Pfam:PF13796"
FT DOMAIN 232..299
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 336..420
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 423 AA; 45335 MW; 12706936A67683B0 CRC64;
MTRLRDAVIA GAQGLYLTIV SLVGSIVLFV FAVLSIAFIL LGIGFFTTPA VLAAVRWYAG
AQRTRAAAWS GVTIPNPYRT YPADLRPGLT GQVERCTRLL KDPATWRDLE WLLVNMTAGP
VVAVFAPALL LYMLYGWVLA LGVWKPIYDA GGGEWFAFIH VTSQSTANQA ALLGMGFFLL
GVLVNPGLVR THFLLSRAFL APTPAMRERQ LAERVDRLTE TRHDAVDNSA AELRRIERDL
HDGAQARLVA MGMDLGTIEA MIETDPAKAK ELIAKARQNS GEALTELRDL VRGIHPPVLA
ERGLGDAVKA LALRLPLPVE VTVELTGRAG APVESAAYFA VSETLTNAIK HAGAERVWVD
MHHADGMLRI AVTDDGKGGA RLGAGSGLAG IERRLGTFDG VLAVSSPAGG PTMVTMEIPC
ELS
//
