ID   A0A0X3W450_9ACTN        Unreviewed;       936 AA.
AC   A0A0X3W450;
DT   13-APR-2016, integrated into UniProtKB/TrEMBL.
DT   13-APR-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=RNA helicase {ECO:0000313|EMBL:KUL51601.1};
GN   ORFNames=ADL30_26815 {ECO:0000313|EMBL:KUL51601.1};
OS   Streptomyces sp. NRRL S-1521.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1609100 {ECO:0000313|EMBL:KUL51601.1, ECO:0000313|Proteomes:UP000053420};
RN   [1] {ECO:0000313|EMBL:KUL51601.1, ECO:0000313|Proteomes:UP000053420}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL S-1521 {ECO:0000313|EMBL:KUL51601.1,
RC   ECO:0000313|Proteomes:UP000053420};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KUL51601.1}.
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DR   EMBL; LLZK01000227; KUL51601.1; -; Genomic_DNA.
DR   RefSeq; WP_062780055.1; NZ_LLZK01000227.1.
DR   AlphaFoldDB; A0A0X3W450; -.
DR   Proteomes; UP000053420; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KUL51601.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053420}.
FT   DOMAIN          44..202
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          283..487
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          252..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          652..685
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   936 AA;  103945 MW;  94B8CA491BDF3D32 CRC64;
     MTEDLSPAER YAAARKRAVE QATALASFRE MYEFGLDPFQ IEACRALEAG KGVLVAAPTG
     SGKTIVGEFA VHLALGQGKK CFYTTPIKAL SNQKYADLAK RYGADKVGLL TGDNSVNSDA
     PVVVMTTEVL RNMLYSGSQA LVNLGYVVMD EVHYLSDRFR GAVWEEVIIH LQESVTLVSL
     SATVSNAEEF GDWLDTVRGD TEVIVSEHRP VPLFQHVLAG RRMYDLFEEG EGRKKAVNPD
     LTRMARLEAS RSYNPRDRRR GKMVREADRE RERRQRSRVW TPGRPEVIER LDSEGLLPAI
     TFIFSRAACE AAVQQCLYAG LRLNDDAARA QVREIVEERT ASIPHEDLHV LGYYEWLEGL
     ERGIAAHHAG MLPTFKEVVE ELFVRGLVKA VFATETLALG INMPARSVVL EKLVKWNGEQ
     HADITPGEYT QLTGRAGRRG IDVEGHAVVL WQRAMNPEHL AGLAGTRTYP LRSSFKPSYN
     MAVNLVEQFG RHRSRELLET SFAQFQADKS VVGISRQVQK NEEGLEGYRA SMTCHLGDFD
     EYARLRRELK DRENELAKQG AVQRRAAAAA SLEKLKPGDV IHVPTGKYAG LALVLDPGLP
     AGRANGHRGF DHVDGPRPLV LTAERQVKRL AAMDFPVPVE ALERMRIPKS FNARSPQSRR
     DLASALRTKA GHIVPDRHRR GRAAAADDQE IARLRTALRS HPCHGCDERE DHARWAERYH
     RLKRDTSQLE RRIEGRTNTI ARTFDRIVAL LGELDYLRGD EVTEHGKRLA RLYGELDLLA
     SECLRAGVWE GLGPAELAAC VSALVYEARV GDDAIAPKVP SGAAKAALGE MVRIWGRLDA
     LEEEFRISQT EGVGQREPDL GFAWAVFMWA NGKGLDEVLR EAEMPAGDFV RWCKQVIDVL
     GQIAAAAPRE GSTVGKNARK AVDQVLRGVV AYSSVG
//